Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PrpT-parD/ParE-CC2985
Location 2486300..2486837 Replicon chromosome
Accession NZ_CP063202
Organism Erythrobacter sp. SCSIO 43205

Toxin (Protein)


Gene name PrpT Uniprot ID -
Locus tag INR77_RS11740 Protein ID WP_223071227.1
Coordinates 2486547..2486837 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag INR77_RS11735 Protein ID WP_223071226.1
Coordinates 2486300..2486554 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
INR77_RS11710 (INR77_11705) 2481741..2482109 - 369 WP_223071222.1 30S ribosomal protein S13 -
INR77_RS15925 2482441..2482926 - 486 WP_255573765.1 hypothetical protein -
INR77_RS15930 2482862..2483209 - 348 WP_255573766.1 hypothetical protein -
INR77_RS11720 (INR77_11715) 2483402..2484049 - 648 WP_223071223.1 adenylate kinase -
INR77_RS11725 (INR77_11720) 2484137..2485501 - 1365 WP_223071224.1 preprotein translocase subunit SecY -
INR77_RS11730 (INR77_11725) 2485649..2486134 - 486 WP_223071225.1 50S ribosomal protein L15 -
INR77_RS11735 (INR77_11730) 2486300..2486554 + 255 WP_223071226.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
INR77_RS11740 (INR77_11735) 2486547..2486837 + 291 WP_223071227.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
INR77_RS11745 (INR77_11740) 2486922..2487329 - 408 WP_223071228.1 hypothetical protein -
INR77_RS11750 (INR77_11745) 2487498..2487950 - 453 WP_223071229.1 hypothetical protein -
INR77_RS11755 (INR77_11750) 2488206..2488382 - 177 WP_223071230.1 50S ribosomal protein L30 -
INR77_RS11760 (INR77_11755) 2488389..2489192 - 804 WP_255573767.1 30S ribosomal protein S5 -
INR77_RS11765 (INR77_11760) 2489192..2489536 - 345 WP_223071231.1 50S ribosomal protein L18 -
INR77_RS11770 (INR77_11765) 2489538..2490071 - 534 WP_223071232.1 50S ribosomal protein L6 -
INR77_RS11775 (INR77_11770) 2490071..2490466 - 396 WP_223071233.1 30S ribosomal protein S8 -
INR77_RS11780 (INR77_11775) 2490478..2490783 - 306 WP_223071234.1 30S ribosomal protein S14 -
INR77_RS11785 (INR77_11780) 2490837..2491415 - 579 WP_223071235.1 50S ribosomal protein L5 -
INR77_RS11790 (INR77_11785) 2491408..2491728 - 321 WP_223071236.1 50S ribosomal protein L24 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-92)

Antitoxin

Antitoxin ParD

(7-71)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11116.66 Da        Isoelectric Point: 8.1045

>T177695 WP_223071227.1 NZ_CP063202:2486547-2486837 [Erythrobacter sp. SCSIO 43205]
MRKLLIGRQADNDLVSISQYTSAEFGESQARKYRDQLRGCFNALLSNPHLGRSAEELAPGLRRIRQQAHVVFYLPTDDEI
LIVRVLHHSMDFERHL

Download         Length: 291 bp

>T177695 NZ_CP083631:c1316235-1314913 [Klebsiella quasipneumoniae]
ATGGCGACGCTCACCACCTGGATGAACAATGCGCGCGTGGGAACCTTAACCCGCCAGGCCAACGGGGCGCACAGTTTCCG
CTATGATGAGGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCGCTGCCGCTGCAGTATGGCAATATTACCG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGAGCGGATCGTCAGGCGCTATCAG
GCGCGTTCGAAACAGCCGTTCGATCTGCTGGCCGAGGTCGGGCGGGACAGCGTAGGGGCGGTGACTCTGCTGCCGCCGGG
GGAAGAGGCGTATCTTGCCGCGTTGCGCTGGCAGACGCTGGATGAGGCGCAGCTGACCGCTTTGCTGACCGCCTACCAGT
CGGATATTCCTCTCGGGATGGTGACCGGCCAGGACGATTTTCGTATCTCGGTGGCCGGCGCTCAGGAGAAAACCGCGCTG
CTGCGAATGGGCGAGCACTGGTGTATTCCGCAGGGCACCACCCCGACCACCCATATCATTAAACTGCCTATCGGCGAGAT
AAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAACGAATATCTGTGCCTGGCGCTGGCCAGGGCGTTGG
GCCTGGCGGTGCCGGAGGCGGAGATTATCAACACGCCGCGGATCCGTGCGCTGGCGGTGACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGGCGCGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCATTCGGCATACCGTCGTCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCCAGTGAGGCCCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTGTTCCAGTGGCTGACCGGGGCAACGGACGGGCATGCGAAGAACTTCTCGCTCTTTTTGCTG
CCCGGCGGCAGCTACCGGCTCACGCCGTTCTACGACATTATTTCGGCATTTCCGGTGCTGGGCGGGACGGGACTGCATCT
GCGCGACCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGGAAAACGGAGATTAACGCTATCTATCCGCGTCATT
TTCTGGCGACCGCCAAAGCGGTTAACTTCCCCCGGGAGCAGATGCTGGCGATCCTGGGCGAGTTTGCCGACCGCGTGCCG
CAGGCCATCGAAAGCGCCCGCCAAACGCTGCCGTCGGACTTTTCCGCCCACGTCTGGCGTGCCATCACGGAGAACATGTT
GAAACTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGGGATAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9527.48 Da        Isoelectric Point: 4.4463

>AT177695 WP_223071226.1 NZ_CP063202:2486300-2486554 [Erythrobacter sp. SCSIO 43205]
MATIRKTITLSDTQDAWIKSQIARGGFTNDSEYIRDLLRRDQEEQTKLSDLREAIAEGLDSGVSERSLDEIWAEGEERAR
KANA

Download         Length: 255 bp

>AT177695 NZ_CP083631:c1316501-1316235 [Klebsiella quasipneumoniae]
ATGAATTCCCCGCAGATATACAGTCCGGTTCAGCTGGCCAATTACCTGAAACTGCTGCGCCAGCAAAATCACTGGACTCA
GGAGGCGCTGGCCAGCCGGATCGGCATTAAACAGGCGACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACCCTGTTTAAGATCCTCCAGTCGCTGGAGGTGGTGATGACCCTGAACGCCAAACCGGCAGAGACGGCGATGATTCCC
GATAACACCACGGATCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References