Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 2312475..2313004 Replicon chromosome
Accession NZ_CP063202
Organism Erythrobacter sp. SCSIO 43205

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag INR77_RS10915 Protein ID WP_223071081.1
Coordinates 2312711..2313004 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag INR77_RS10910 Protein ID WP_223071080.1
Coordinates 2312475..2312714 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
INR77_RS10890 (INR77_10885) 2307983..2308534 + 552 WP_223071077.1 hypothetical protein -
INR77_RS10895 (INR77_10890) 2308611..2310275 - 1665 WP_223071078.1 M56 family metallopeptidase -
INR77_RS10900 (INR77_10895) 2310272..2310655 - 384 WP_255573748.1 BlaI/MecI/CopY family transcriptional regulator -
INR77_RS10905 (INR77_10900) 2310797..2312374 + 1578 WP_223071079.1 peptidylprolyl isomerase -
INR77_RS10910 (INR77_10905) 2312475..2312714 + 240 WP_223071080.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
INR77_RS10915 (INR77_10910) 2312711..2313004 + 294 WP_223071081.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
INR77_RS10920 (INR77_10915) 2313016..2313591 - 576 WP_223071082.1 hypothetical protein -
INR77_RS10925 (INR77_10920) 2313709..2315541 - 1833 WP_223071083.1 succinate dehydrogenase flavoprotein subunit -
INR77_RS10930 (INR77_10925) 2315541..2315927 - 387 WP_223071084.1 succinate dehydrogenase, hydrophobic membrane anchor protein -
INR77_RS10935 (INR77_10930) 2315931..2316320 - 390 WP_223071085.1 succinate dehydrogenase, cytochrome b556 subunit -
INR77_RS10940 (INR77_10935) 2316430..2317155 + 726 WP_223071086.1 SDR family oxidoreductase -
INR77_RS10945 (INR77_10940) 2317240..2317509 + 270 WP_255573749.1 GIY-YIG nuclease family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(4-71)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10983.70 Da        Isoelectric Point: 11.7835

>T177694 WP_223071081.1 NZ_CP063202:2312711-2313004 [Erythrobacter sp. SCSIO 43205]
MTRKVVFRTAAKRDLSQLGAQSAREWGARRTRGYLLDLDAKIQKLAENPMLGHEAGLGRAGVRRMNSGRHAVFYVVGEER
IEIVRILHVSRDAGRWV

Download         Length: 294 bp

>T177694 NZ_CP083631:630467-630569 [Klebsiella quasipneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8971.85 Da        Isoelectric Point: 4.1734

>AT177694 WP_223071080.1 NZ_CP063202:2312475-2312714 [Erythrobacter sp. SCSIO 43205]
MGKNTSVSLGEHFEEYTRSKVATGEYSSTSEVIREALRLHEERSVFKSKLLEAIDEGLASPIDESFDMDAWINETFPEE

Download         Length: 240 bp

>AT177694 NZ_CP083631:c630573-630426 [Klebsiella quasipneumoniae]
AGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGTCTGCG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References