Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1004580..1005597 Replicon chromosome
Accession NZ_CP063202
Organism Erythrobacter sp. SCSIO 43205

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag INR77_RS04735 Protein ID WP_223072790.1
Coordinates 1005220..1005597 (+) Length 126 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag INR77_RS04730 Protein ID WP_223072788.1
Coordinates 1004580..1005227 (+) Length 216 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
INR77_RS04700 (INR77_04700) 1000201..1000470 - 270 WP_223072780.1 hypothetical protein -
INR77_RS04705 (INR77_04705) 1000680..1001624 - 945 WP_223072781.1 DUF2493 domain-containing protein -
INR77_RS04710 (INR77_04710) 1001902..1002630 - 729 WP_223072782.1 RES family NAD+ phosphorylase -
INR77_RS04715 (INR77_04715) 1002602..1002979 - 378 WP_223072784.1 MbcA/ParS/Xre antitoxin family protein -
INR77_RS04720 (INR77_04720) 1003020..1003448 - 429 WP_223072785.1 hypothetical protein -
INR77_RS04725 (INR77_04725) 1003460..1004389 - 930 WP_223072787.1 zincin-like metallopeptidase domain-containing protein -
INR77_RS04730 (INR77_04730) 1004580..1005227 + 648 WP_223072788.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
INR77_RS04735 1005220..1005597 + 378 WP_223072790.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
INR77_RS04740 1005573..1006073 + 501 WP_223072792.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
INR77_RS15860 1006691..1006819 + 129 WP_255573939.1 hypothetical protein -
INR77_RS15865 1006906..1007160 + 255 WP_255573940.1 type II toxin-antitoxin system RelE/ParE family toxin -
INR77_RS04750 (INR77_04745) 1007272..1007601 + 330 WP_223072793.1 DNA-binding transcriptional regulator -
INR77_RS04755 (INR77_04750) 1007727..1008626 - 900 WP_223072794.1 pirin-like C-terminal cupin domain-containing protein -
INR77_RS04760 (INR77_04755) 1008778..1009497 - 720 WP_223072795.1 type II CAAX endopeptidase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - gmd / fcl 880059..1005846 125787


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-109)

Antitoxin

Transcriptional regulator AbiEi antitoxin, N-terminal domain

(18-101)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14001.06 Da        Isoelectric Point: 5.1976

>T177693 WP_223072790.1 NZ_CP063202:1005220-1005597 [Erythrobacter sp. SCSIO 43205]
MADGPRNMAASVKARLLAMSGEEGRAFDLLLVRYALERLLFRLSVSPHRGNYMLKGGMLVTQWLEHGNRETRDIDFLGFG
ANDEEAIKAIFAEIMTTETGDGLVFDIETWWQARSAMKWSMAASA

Download         Length: 378 bp

>T177693 NZ_CP083630:5010169-5010582 [Leclercia adecarboxylata]
GTGGTCCTGTGGCAATCTGATTTACGCGTCTCGTGGCGCGCCCAGTGGATGTCTCTTTTGCTCCACGGCCTGGTTGCGGC
TTGCATCCTGTTGATACCATGGCCGCTAAGCTACACCCCGTTATGGTTAATTTTACTGTCGCTGGTGGTGTTTGACAGCG
TACGCAGCCAACGGCGCATCAATTCCCGCCAGGGCGAAATCAAGCTATTCATGGATTCCCGCCTGCAGTGGCAGGGTAGC
GAGTGGGAGATTATCGGTACGCCGTGGATGCTCAATTCCGGCATGATGCTCCGCTTACGCAAGGGCGACGGGAAACGCTA
CCAGCATTTGTGGTTGTCGGCAGACAGCATGGATGAAGGGGAGTGGCGGGATCTGCGCCGGATGCTTTCGCAGCAACCGA
CGCACGGGCGGTAG

Antitoxin


Download         Length: 216 a.a.        Molecular weight: 23893.55 Da        Isoelectric Point: 10.0654

>AT177693 WP_223072788.1 NZ_CP063202:1004580-1005227 [Erythrobacter sp. SCSIO 43205]
MNFSYRFLNEMVEAINQREKLRTLVKAGTILRAQDLREQGIAGTTIRRALNDGELLRIGRGLYQNPDADIDSDLTIAEIS
TRIPKGVIAMVSALAWHGLTDQMPRKTWVAIGTNDWKPVEGSPPVRIVRFADKYLTQGIEHHTICGIDVPIYSVPKTLAD
LFRNGKLVDRSVAVEGLRAAVEQRKATPSAIAEAARKGGAWRIMRPYLEALTFNG

Download         Length: 648 bp

>AT177693 NZ_CP083630:5009922-5010188 [Leclercia adecarboxylata]
ATGGACATTACTAACAAAGCCCGCATTCATTGGGCATGCCGTCGCGGTATGCGCGAACTCGATATCTCCATCATGCCGTT
CTTCGAATACGAATACGACACCCTGAGCGATGAGGATAAAAAGCTGTTTATCCGCCTGCTGGAGAACGACGATCCTGATT
TATTTAACTGGTTAATGAATCACGGCGAACCCGCCGACGCCGAACTGCAACGGATGGTGCTTTTAATTCAAACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References