Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2507304..2507575 Replicon chromosome
Accession NZ_CP063153
Organism Escherichia coli strain M7424

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2507342..2507445 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2507304..2507575 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
INR48_RS11895 2504461..2505900 + 1440 WP_188926226.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
INR48_RS11900 2506018..2506254 + 237 WP_001295499.1 DUF1480 family protein -
INR48_RS11905 2506359..2506550 + 192 WP_001296140.1 YebW family protein -
INR48_RS11910 2506551..2507207 - 657 WP_000812712.1 protein-serine/threonine phosphatase -
- 2507304..2507575 + 272 - - Antitoxin
- 2507342..2507445 - 104 - - Toxin
INR48_RS11915 2507603..2507944 - 342 WP_000976481.1 YebY family protein -
INR48_RS11920 2507957..2508829 - 873 WP_000879330.1 copper homeostasis membrane protein CopD -
INR48_RS11925 2508833..2509207 - 375 WP_000168743.1 CopC domain-containing protein YobA -
INR48_RS11930 2509346..2509576 + 231 WP_000916763.1 DNA polymerase III subunit theta -
INR48_RS11935 2509678..2510334 + 657 WP_000011654.1 carbon-nitrogen hydrolase family protein -
INR48_RS11940 2510358..2511020 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2501748..2514884 13136


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T177648 NZ_CP063153:c2507445-2507342 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT177648 NZ_CP063153:2507304-2507575 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References