Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1981465..1981610 Replicon chromosome
Accession NZ_CP063147
Organism Klebsiella pneumoniae strain KP19-3088

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1981501..1981603 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1981465..1981610 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IMY63_RS09685 1976595..1978655 + 2061 WP_004151449.1 oligopeptidase B -
IMY63_RS09690 1978659..1979318 - 660 WP_021440386.1 exodeoxyribonuclease X -
IMY63_RS09695 1979397..1979627 - 231 WP_002911406.1 DNA polymerase III subunit theta -
IMY63_RS09700 1979740..1980114 + 375 WP_004151448.1 CopC domain-containing protein YobA -
IMY63_RS09705 1980118..1980987 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
IMY63_RS09710 1981004..1981342 + 339 WP_002911404.1 YebY family protein -
- 1981465..1981610 - 146 - - Antitoxin
- 1981501..1981603 + 103 - - Toxin
IMY63_RS09715 1981978..1982121 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
IMY63_RS09720 1982226..1983194 - 969 WP_004151446.1 VirK/YbjX family protein -
IMY63_RS09725 1983351..1984004 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
IMY63_RS09730 1984001..1984192 - 192 WP_002911395.1 YebW family protein -
IMY63_RS09735 1984290..1984529 - 240 WP_002911393.1 YebV family protein -
IMY63_RS09740 1984645..1986078 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T177602 NZ_CP063147:1981501-1981603 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT177602 NZ_CP063147:c1981610-1981465 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References