Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 413187..413698 Replicon chromosome
Accession NZ_CP063145
Organism Cruoricaptor ignavus strain M1214

Toxin (Protein)


Gene name relE Uniprot ID A0A1M6BJ90
Locus tag IMZ16_RS01875 Protein ID WP_073178066.1
Coordinates 413187..413444 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A1M6BJC3
Locus tag IMZ16_RS01880 Protein ID WP_073178064.1
Coordinates 413444..413698 (-) Length 85 a.a.

Genomic Context

IMZ16_RS01890IMZ16_RS01895IMZ16_RS01900IMZ16_RS01850IMZ16_RS01855IMZ16_RS01860IMZ16_RS01865IMZ16_RS01870IMZ16_RS01875IMZ16_RS01880IMZ16_RS01885IMZ16_RS01905
Location: 415208..415393 (186 bp)
Type: Others
Protein ID: WP_193440261.1
Location: 415781..416050 (270 bp)
Type: Others
Protein ID: WP_193439832.1
Location: 416082..416909 (828 bp)
Type: Others
Protein ID: WP_193439181.1
Location: 408785..410437 (1653 bp)
Type: Others
Protein ID: WP_073178051.1
Location: 410485..411087 (603 bp)
Type: Others
Protein ID: WP_193440256.1
Location: 411084..411458 (375 bp)
Type: Others
Protein ID: WP_193440257.1
Location: 411957..412424 (468 bp)
Type: Others
Protein ID: WP_193440258.1
Location: 412911..413108 (198 bp)
Type: Others
Protein ID: WP_193440259.1
Location: 413187..413444 (258 bp)
Type: Toxin
Protein ID: WP_073178066.1
Location: 413444..413698 (255 bp)
Type: Antitoxin
Protein ID: WP_073178064.1
Location: 413855..414922 (1068 bp)
Type: Others
Protein ID: WP_193440260.1
Location: 417402..417629 (228 bp)
Type: Others
Protein ID: WP_193440262.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
IMZ16_RS01850408785..410437-1653WP_073178051.1mercury(II) reductase-
IMZ16_RS01855410485..411087-603WP_193440256.1mercuric transport protein MerTP-
IMZ16_RS01860411084..411458-375WP_193440257.1metalloregulator ArsR/SmtB family transcription factor-
IMZ16_RS01865411957..412424-468WP_193440258.1hypothetical protein-
IMZ16_RS01870412911..413108-198WP_193440259.1hypothetical protein-
IMZ16_RS01875413187..413444-258WP_073178066.1Txe/YoeB family addiction module toxinToxin
IMZ16_RS01880413444..413698-255WP_073178064.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
IMZ16_RS01885413855..414922-1068WP_193440260.1nitronate monooxygenase family protein-
IMZ16_RS01890415208..415393+186WP_193440261.1hypothetical protein-
IMZ16_RS01895415781..416050+270WP_193439832.1transposase-
IMZ16_RS01900416082..416909+828WP_193439181.1IS3 family transposase-
IMZ16_RS01905417402..417629-228WP_193440262.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--397780..41717019390


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10632.08 Da        Isoelectric Point: 8.7763

>T177596 WP_073178066.1 NZ_CP063145:c413444-413187 [Cruoricaptor ignavus]
MRYVFVDESWEDYLYWQKTDKKKLKRINDLLKDISRNPFEGIGKPEPLKHKYSGFWSRRIDDEHRLIYRYEEGEIQIAKC
RFHYD

Download         Length: 258 bp

>T177596 NZ_CP083585:3547494-3547712 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9539.94 Da        Isoelectric Point: 7.0124

>AT177596 WP_073178064.1 NZ_CP063145:c413698-413444 [Cruoricaptor ignavus]
MLIASVSDFRKDIKTYLDKVAKNFETLIISRGKDSGIVVMSLNEYNSLMATNHELSTRANELRLDSAIDKLKSKNSFEKT
LIEE

Download         Length: 255 bp

>AT177596 NZ_CP083585:3547094-3547468 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACTCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1M6BJ90

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1M6BJC3

References