Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | shpAB/BrnT-BrnA |
Location | 1372533..1373041 | Replicon | chromosome |
Accession | NZ_CP063046 | ||
Organism | Escherichia coli strain KC-Dl-1 |
Toxin (Protein)
Gene name | shpA | Uniprot ID | - |
Locus tag | IL980_RS06660 | Protein ID | WP_001534843.1 |
Coordinates | 1372832..1373041 (-) | Length | 70 a.a. |
Antitoxin (Protein)
Gene name | shpB | Uniprot ID | A0A0V9L4L3 |
Locus tag | IL980_RS06655 | Protein ID | WP_000063161.1 |
Coordinates | 1372533..1372835 (-) | Length | 101 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IL980_RS06640 | 1369061..1371211 | + | 2151 | WP_001366791.1 | pyruvate/proton symporter BtsT | - |
IL980_RS06645 | 1371329..1371532 | + | 204 | WP_001534846.1 | YbdD/YjiX family protein | - |
IL980_RS06650 | 1371543..1372499 | + | 957 | WP_001534845.1 | GTPase | - |
IL980_RS06655 | 1372533..1372835 | - | 303 | WP_000063161.1 | BrnA antitoxin family protein | Antitoxin |
IL980_RS06660 | 1372832..1373041 | - | 210 | WP_001534843.1 | BrnT family toxin | Toxin |
IL980_RS06665 | 1373137..1374303 | + | 1167 | WP_197613138.1 | restriction endonuclease | - |
IL980_RS06670 | 1374367..1375985 | + | 1619 | Protein_1302 | type I restriction-modification system subunit M | - |
IL980_RS06675 | 1375975..1377285 | + | 1311 | WP_001534837.1 | restriction endonuclease subunit S | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 70 a.a. Molecular weight: 7952.17 Da Isoelectric Point: 4.9493
>T177540 WP_001534843.1 NZ_CP063046:c1373041-1372832 [Escherichia coli]
MVDYPKRDAISNINAIIVDTFLYIQLGMATMPMEFEWNANKAKSNRVKHGIRFEDAVLVLDDPQRTEPL
MVDYPKRDAISNINAIIVDTFLYIQLGMATMPMEFEWNANKAKSNRVKHGIRFEDAVLVLDDPQRTEPL
Download Length: 210 bp
>T177540 NZ_CP083530:c1611567-1611460 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTCTGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTCTGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA
Antitoxin
Download Length: 101 a.a. Molecular weight: 11600.10 Da Isoelectric Point: 9.4646
>AT177540 WP_000063161.1 NZ_CP063046:c1372835-1372533 [Escherichia coli]
MSMVKHKRGTSSTLDVQHEAELKVLANKFDEDIDYSDIPSSSDEQWSNAERGKFYRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLRDQNKK
MSMVKHKRGTSSTLDVQHEAELKVLANKFDEDIDYSDIPSSSDEQWSNAERGKFYRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLRDQNKK
Download Length: 303 bp
>AT177540 NZ_CP083530:1611615-1611681 [Escherichia coli]
GGTCTAGATGCAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT
GGTCTAGATGCAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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