Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1982531..1982676 Replicon chromosome
Accession NZ_CP063019
Organism Klebsiella pneumoniae strain CriePir75

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1982567..1982669 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1982531..1982676 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GJJ10_RS09620 1977661..1979721 + 2061 WP_004151449.1 oligopeptidase B -
GJJ10_RS09625 1979725..1980384 - 660 WP_002911407.1 exodeoxyribonuclease X -
GJJ10_RS09630 1980463..1980693 - 231 WP_002911406.1 DNA polymerase III subunit theta -
GJJ10_RS09635 1980806..1981180 + 375 WP_004151448.1 CopC domain-containing protein YobA -
GJJ10_RS09640 1981184..1982053 + 870 WP_019725445.1 copper homeostasis membrane protein CopD -
GJJ10_RS09645 1982070..1982408 + 339 WP_002911404.1 YebY family protein -
- 1982531..1982676 - 146 - - Antitoxin
- 1982567..1982669 + 103 - - Toxin
GJJ10_RS09650 1983044..1983187 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
GJJ10_RS09655 1983292..1984260 - 969 WP_004151446.1 VirK/YbjX family protein -
GJJ10_RS09660 1984417..1985070 + 654 WP_019725444.1 protein-serine/threonine phosphatase -
GJJ10_RS09665 1985067..1985258 - 192 WP_002911395.1 YebW family protein -
GJJ10_RS09670 1985356..1985595 - 240 WP_002911393.1 YebV family protein -
GJJ10_RS09675 1985711..1987144 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T177503 NZ_CP063019:1982567-1982669 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT177503 NZ_CP063019:c1982676-1982531 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References