Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2069551..2069696 Replicon chromosome
Accession NZ_CP063008
Organism Klebsiella pneumoniae strain CriePir120

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2069587..2069689 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2069551..2069696 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GJJ08_RS10105 2064681..2066741 + 2061 WP_004148850.1 oligopeptidase B -
GJJ08_RS10110 2066745..2067404 - 660 WP_032435029.1 exodeoxyribonuclease X -
GJJ08_RS10115 2067483..2067713 - 231 WP_002911406.1 DNA polymerase III subunit theta -
GJJ08_RS10120 2067826..2068200 + 375 WP_004151448.1 CopC domain-containing protein YobA -
GJJ08_RS10125 2068204..2069073 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
GJJ08_RS10130 2069090..2069428 + 339 WP_002911404.1 YebY family protein -
- 2069551..2069696 - 146 - - Antitoxin
- 2069587..2069689 + 103 - - Toxin
GJJ08_RS10135 2070064..2070207 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
GJJ08_RS10140 2070312..2071280 - 969 WP_004151446.1 VirK/YbjX family protein -
GJJ08_RS10145 2071437..2072090 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
GJJ08_RS10150 2072087..2072278 - 192 WP_002911395.1 YebW family protein -
GJJ08_RS10155 2072376..2072615 - 240 WP_002911393.1 YebV family protein -
GJJ08_RS10160 2072731..2074164 - 1434 WP_073546008.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T177467 NZ_CP063008:2069587-2069689 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT177467 NZ_CP063008:c2069696-2069551 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References