Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1940479..1940623 Replicon chromosome
Accession NZ_CP063003
Organism Klebsiella pneumoniae strain CriePir154

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1940515..1940617 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1940479..1940623 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GJI94_RS09385 1935609..1937669 + 2061 WP_004151449.1 oligopeptidase B -
GJI94_RS09390 1937673..1938332 - 660 WP_002911407.1 exodeoxyribonuclease X -
GJI94_RS09395 1938411..1938641 - 231 WP_002911406.1 DNA polymerase III subunit theta -
GJI94_RS09400 1938754..1939128 + 375 WP_004151448.1 CopC domain-containing protein YobA -
GJI94_RS09405 1939132..1940001 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
GJI94_RS09410 1940018..1940356 + 339 WP_002911404.1 YebY family protein -
- 1940479..1940623 - 145 - - Antitoxin
- 1940515..1940617 + 103 - - Toxin
GJI94_RS09415 1940750..1941109 - 360 WP_077253379.1 tyrosine-type recombinase/integrase -
GJI94_RS09420 1941108..1941587 + 480 WP_032419797.1 lysis protein -
GJI94_RS09425 1942376..1943881 + 1506 WP_020956680.1 hypothetical protein -
GJI94_RS09430 1944131..1944559 - 429 WP_032419788.1 type II toxin-antitoxin system PemK/MazF family toxin -
GJI94_RS09435 1944569..1944850 - 282 WP_032419786.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T177448 NZ_CP063003:1940515-1940617 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT177448 NZ_CP063003:c1940623-1940479 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References