Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1884584..1884729 Replicon chromosome
Accession NZ_CP062986
Organism Klebsiella pneumoniae strain CriePir26

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1884620..1884722 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1884584..1884729 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GJJ26_RS09155 (GJJ26_009155) 1879714..1881774 + 2061 WP_004148850.1 oligopeptidase B -
GJJ26_RS09160 (GJJ26_009160) 1881778..1882437 - 660 WP_002911407.1 exodeoxyribonuclease X -
GJJ26_RS09165 (GJJ26_009165) 1882516..1882746 - 231 WP_002911406.1 DNA polymerase III subunit theta -
GJJ26_RS09170 (GJJ26_009170) 1882859..1883233 + 375 WP_071058708.1 CopC domain-containing protein YobA -
GJJ26_RS09175 (GJJ26_009175) 1883237..1884106 + 870 WP_032420215.1 copper homeostasis membrane protein CopD -
GJJ26_RS09180 (GJJ26_009180) 1884123..1884461 + 339 WP_002911404.1 YebY family protein -
- 1884584..1884729 - 146 - - Antitoxin
- 1884620..1884722 + 103 - - Toxin
GJJ26_RS09185 (GJJ26_009185) 1885097..1885240 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
GJJ26_RS09190 (GJJ26_009190) 1885345..1886313 - 969 WP_073971755.1 VirK/YbjX family protein -
GJJ26_RS09195 (GJJ26_009195) 1886470..1887123 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
GJJ26_RS09200 (GJJ26_009200) 1887120..1887311 - 192 WP_002911395.1 YebW family protein -
GJJ26_RS09205 (GJJ26_009205) 1887409..1887648 - 240 WP_002911393.1 YebV family protein -
GJJ26_RS09210 (GJJ26_009210) 1887764..1889197 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T177404 NZ_CP062986:1884620-1884722 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT177404 NZ_CP062986:c1884729-1884584 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References