Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1415465..1416054 Replicon chromosome
Accession NZ_CP062951
Organism Bifidobacterium longum subsp. infantis strain JCM 11347

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag BL1347_RS06285 Protein ID WP_193641245.1
Coordinates 1415746..1416054 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BL1347_RS06280 Protein ID WP_193641244.1
Coordinates 1415465..1415749 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BL1347_RS06250 1410826..1411734 + 909 WP_193641239.1 ABC transporter ATP-binding protein -
BL1347_RS06255 1411731..1412462 + 732 WP_193641240.1 ABC transporter permease -
BL1347_RS06260 1412848..1414116 + 1269 WP_193641241.1 YcaO-like family protein -
BL1347_RS06265 1414070..1414762 + 693 WP_193641242.1 hypothetical protein -
BL1347_RS06270 1414866..1415198 - 333 WP_193641243.1 hypothetical protein -
BL1347_RS06280 1415465..1415749 - 285 WP_193641244.1 putative addiction module antidote protein Antitoxin
BL1347_RS06285 1415746..1416054 - 309 WP_193641245.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BL1347_RS06290 1416086..1416437 - 352 Protein_1218 DUF1922 domain-containing protein -
BL1347_RS06295 1416542..1417030 + 489 WP_193641246.1 D-tyrosyl-tRNA(Tyr) deacylase -
BL1347_RS06300 1417191..1420310 + 3120 WP_193641247.1 alpha-mannosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-97)

Antitoxin

Uncharacterized protein HI1420

(5-91)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11592.35 Da        Isoelectric Point: 10.3171

>T177358 WP_193641245.1 NZ_CP062951:c1416054-1415746 [Bifidobacterium longum subsp. infantis]
VEIKQSAEYRKWFKKLRDHKAKAAIQARLDACKLAGRPFGGIKPVEGPVSEMRFHTGAGYRVYFAMQGNVLMLLLAGGDK
STQQTDIRQAHDILNDYKEQRQ

Download         Length: 309 bp

>T177358 NZ_CP083451:c4195027-4194149 [Comamonas odontotermitis]
ATGACCACCGACACCGCCACCCTCTGGAGTGAAGCGCTCATGCGCAAGGCGCAACAGCTGGAATCGCAGTTCGCGCAGCG
CTCGGTAGCGCTGCCCGATGGCGTGCAGCTGGCTGTGCGCGAGCGCCCGGCCGCCGGTGTTGCCGCGCAGACCGTAGTGC
TGCTGCATGGCATCAGCTCGTCGGCGGCCTCGTGGCTGGATGTGGCATTGGCGCTACGCCCTGACTGGCGCGTGCTGGCC
TGGGATGCGCCCGGCTATGGTTCGAGCACAGCCCTGCCGCAGACCCATCCGCACGATACCGACTATGCCGCACGTCTGGG
CGCCTGGCTGGCCGCAGAGGTGCGGGGCCCAGTGGTGCTGGTGGGCCATTCCCTGGGGGCGTTGATGGCAGCGGCCTGCG
CTGCGCAATACGCACCCCAGGCGCTGGCAGGCGTGCTATTGCTCAGCCCTGCTGGCGGCTATGGCTCGCACGATGTAGCT
GCCCGCGAAAAGGTGCGCAGCGAGCGCAATGCCTCGCTCGACACGCTGGGCGTGGCGGGCCTTGCGCAACGCATCGACCA
GCGACTGCTCAGTCCTGGCGCGGACGCACTGGCGCGCGAGTGGGTGCGCTGGAGCACATCGCGCATGCACGATGGCGGCT
ACCGCCAGGCCGTGAACATGCTGTGCGACAGCGACCTGGGCAGGCATGCGCCGCTGCCCGTGCCTGTGCACATTGCTTGT
GGCGAGCACGATGTGGTCACCACCCCTGCAGCCTGCCGCCGCTGGGCCGGAGCCTGGCAGGTGCCTTTTTCCAGCATCGC
TGATGCAGGCCATGCCAGTCCGGTTGAAAAACCCGGCGCGGTGGCCGAATGGATCGAAGATAGAGCCTTCTTACTTTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10174.37 Da        Isoelectric Point: 4.3707

>AT177358 WP_193641244.1 NZ_CP062951:c1415749-1415465 [Bifidobacterium longum subsp. infantis]
MSTEFTDYDTSEYLENEQDIIAYLNAIAEYDDPALMQAALGNVAKSRGMTQIAKDAGVGRESLYKSLSKDGNPSFQTIAK
VIHALGGRLTIQAA

Download         Length: 285 bp

>AT177358 NZ_CP083451:c4194133-4193297 [Comamonas odontotermitis]
ATGACACAGACCAACCCTTCCGAAACCGGCTCTGAAAAGTACGTGGTGCCAGCGCTGGAGCGCGGATTGCGCCTGCTGCA
GGAGTTTGGCCGCGACAGCCGCACCCTGGGCGCCCCGGAGCTGGCGCGCCGACTGGAGCTGCCCCGTGCCACGGTGTTCC
GCATGCTCAACACGCTAGAAGGCATGGGCTTTCTGGAGCGCATCGACGGCGGCACCGAATACCGTCTCGGCATGGCCGTG
CTGCGCCTGGGCTTCGAGTACCTGTCGTCCCTGGAGCTGACGGAGCTGGGCCAGCCTGTCATCGCCCGCTTGTGCGACGA
AATCAGCTACCCCTGCAATATCGTGGTGCGAGACAACCGCTCGATTGTCTACGTCGCCAAGGTCACGCCGCCGCGGCCTC
TGGCCAGCGCCGTGCACGTAGGCACCCGGCTGGCGGCGCACGGCACGGTTTTCGGCCGTGTGCTGCTCCTGGACTTTTCA
TTGGCGGAACTGCGCGCGCTCTACCCGGAAGAGCATCTGGAAGCGTTCTCGCCGAACACCCCCAGAACCGCGCTCGACCT
GTTCAACCTGATCGAGGTCGACCGCGAGCGCGGCTACGTCTTCGGTGAGGGCTTTTACGAAACCTCGATCTCCACCGTCG
CGGCGCCCGTGCGTGACCACAGCGGTCGCATCGTGGCTGCGCTGGGCTCCACGATTCCGTCACCGCATGCGGGTCAGGCC
AAGGCAGCAGGCGTCGCCGAGCGTGTATGTGCAGCAGCCGATGAGCTCTCGGGCCTGCTGAACTACCGCCGTGAGGCACA
AGCCGGTGCCCGGGTTCTGTCCATGCCGGGACATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References