Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2628189..2628714 Replicon chromosome
Accession NZ_CP062946
Organism Thalassotalea sp. LPB0316

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP316_RS11755 Protein ID WP_193021351.1
Coordinates 2628189..2628476 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP316_RS11760 Protein ID WP_193021352.1
Coordinates 2628466..2628714 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP316_RS11710 2623254..2623556 + 303 WP_193021342.1 hypothetical protein -
LP316_RS11715 2623662..2624045 + 384 WP_193021341.1 hypothetical protein -
LP316_RS11720 2624159..2624671 + 513 WP_193021344.1 hypothetical protein -
LP316_RS11725 2624791..2625000 + 210 WP_193021345.1 hypothetical protein -
LP316_RS11730 2625117..2625479 + 363 WP_193021346.1 hypothetical protein -
LP316_RS11735 2625596..2625814 + 219 WP_193021347.1 hypothetical protein -
LP316_RS11740 2625962..2626264 + 303 WP_193021348.1 hypothetical protein -
LP316_RS11745 2626383..2626712 + 330 WP_193021349.1 hypothetical protein -
LP316_RS11750 2626906..2627094 + 189 WP_193021350.1 hypothetical protein -
LP316_RS11755 2628189..2628476 - 288 WP_193021351.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP316_RS11760 2628466..2628714 - 249 WP_193021352.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LP316_RS11765 2628883..2629119 + 237 WP_193021353.1 hypothetical protein -
LP316_RS11770 2629248..2629664 + 417 WP_193023891.1 hypothetical protein -
LP316_RS11775 2629778..2630494 + 717 WP_193021354.1 subclass B1 metallo-beta-lactamase -
LP316_RS11780 2630676..2630927 + 252 WP_193021355.1 TIGR03643 family protein -
LP316_RS11785 2631065..2631472 + 408 WP_193021356.1 PH domain-containing protein -
LP316_RS11790 2631582..2632298 + 717 WP_193021357.1 CPBP family intramembrane metalloprotease -
LP316_RS11795 2632552..2633166 + 615 WP_193021358.1 hypothetical protein -
LP316_RS11800 2633340..2633711 + 372 WP_193021359.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2593163..2683525 90362


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-81)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-73)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10899.87 Da        Isoelectric Point: 10.5040

>T177349 WP_193021351.1 NZ_CP062946:c2628476-2628189 [Thalassotalea sp. LPB0316]
MSYELEFKKSALKEWKKLGATIQTQFKKKLAEILVNPHIPSAKLSGANELYKIKLRQAGYRLVYEVNDEIITVTVISVGK
RDKGKVYKVAMKRND

Download         Length: 288 bp

>T177349 NZ_CP083445:c5191325-5190003 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCACTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCAGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
AAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCGCCACTCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCGGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9213.53 Da        Isoelectric Point: 4.1443

>AT177349 WP_193021352.1 NZ_CP062946:c2628714-2628466 [Thalassotalea sp. LPB0316]
MTTRILTETAASISELKANPMKVALSANGEPIAILNRNEPAFYCIPAETYEFLMDHLEDLELMQIAESRKNEESIKVSLD
EL

Download         Length: 249 bp

>AT177349 NZ_CP083445:c5191591-5191325 [Klebsiella pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGACGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References