Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 2572153..2572663 Replicon chromosome
Accession NZ_CP062946
Organism Thalassotalea sp. LPB0316

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP316_RS11485 Protein ID WP_193021303.1
Coordinates 2572400..2572663 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP316_RS11480 Protein ID WP_193021302.1
Coordinates 2572153..2572407 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP316_RS11445 2567893..2568480 - 588 WP_193021296.1 hypothetical protein -
LP316_RS11450 2568407..2568589 + 183 Protein_2211 transposase -
LP316_RS11455 2568675..2569367 - 693 WP_193021297.1 hypothetical protein -
LP316_RS11460 2569387..2570076 - 690 WP_193021298.1 hypothetical protein -
LP316_RS11465 2570537..2571148 - 612 WP_193021299.1 tyrosine-type recombinase/integrase -
LP316_RS11470 2571238..2571570 + 333 WP_193021300.1 type II toxin-antitoxin system RelE/ParE family toxin -
LP316_RS11475 2571557..2571871 + 315 WP_193021301.1 DNA-binding transcriptional regulator -
LP316_RS11480 2572153..2572407 + 255 WP_193021302.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LP316_RS11485 2572400..2572663 + 264 WP_193021303.1 Txe/YoeB family addiction module toxin Toxin
LP316_RS11490 2572869..2574185 - 1317 WP_193021304.1 thymidine phosphorylase -
LP316_RS11495 2574195..2574590 - 396 WP_193021305.1 cytidine deaminase -
LP316_RS11500 2574824..2576569 - 1746 WP_193021306.1 DUF3466 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10327.64 Da        Isoelectric Point: 6.7148

>T177348 WP_193021303.1 NZ_CP062946:2572400-2572663 [Thalassotalea sp. LPB0316]
MTNRLLSWTDEAWDPYLYWQTQDNKTLKRINKLVTDVKRSPFEGIGKLEPLKENLTSFWSSRIDDTNRLVNAVDDHAITI
ISCHYHY

Download         Length: 264 bp

>T177348 NZ_CP083445:4456949-4457051 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9509.62 Da        Isoelectric Point: 5.5720

>AT177348 WP_193021302.1 NZ_CP062946:2572153-2572407 [Thalassotalea sp. LPB0316]
MRIVSFTEARNSLKAVLDGIVNDADTTAITRRDSEDAIVMSLDYYNSLMETVHLLRSPANTEHLNRSISQYKSGKVNHRD
LIDD

Download         Length: 255 bp

>AT177348 NZ_CP083445:c4457058-4456913 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References