Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 2331426..2331960 Replicon chromosome
Accession NZ_CP062946
Organism Thalassotalea sp. LPB0316

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP316_RS10330 Protein ID WP_193020929.1
Coordinates 2331679..2331960 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP316_RS10325 Protein ID WP_193020927.1
Coordinates 2331426..2331692 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP316_RS10310 2328016..2328624 - 609 WP_193020923.1 rhombosortase -
LP316_RS10315 2328774..2329436 + 663 WP_193023881.1 DTW domain-containing protein -
LP316_RS10320 2329440..2331209 + 1770 WP_193020925.1 gamma-glutamyltransferase -
LP316_RS10325 2331426..2331692 + 267 WP_193020927.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP316_RS10330 2331679..2331960 + 282 WP_193020929.1 type II toxin-antitoxin system YafQ family toxin Toxin
LP316_RS10335 2332114..2332545 - 432 WP_193020931.1 hypothetical protein -
LP316_RS10340 2332679..2333644 - 966 WP_193020932.1 cysteine synthase A -
LP316_RS10345 2333797..2334642 + 846 WP_193020934.1 MoxR family ATPase -
LP316_RS10350 2334646..2335818 + 1173 WP_193020936.1 VWA domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-93)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-79)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10896.68 Da        Isoelectric Point: 9.2036

>T177346 WP_193020929.1 NZ_CP062946:2331679-2331960 [Thalassotalea sp. LPB0316]
VLKIRTKSSFKKDLKRAAKNNRHNTKLLKELIDKHLIITGTVPSQYKPHLLQGNWQPHMECHIQPDFLLIWDVDWEAEEL
ILVRCGSHSELFG

Download         Length: 282 bp

>T177346 NZ_CP083445:3359772-3360257 [Klebsiella pneumoniae]
ATGATCTCGGCACCAGAACCGCTTCATGCCGGGCATATTCTTACCCCGTTTTGCTGCGGTATAGATTCCATGGATCACTG
GCTGAAACAGCGGGCGATGAAAAATCAGGTTACTGGCGCATCCCGCACCTTTGTCTGCTGCGACGACGCGAAGGTGATGG
CTTACTACTCACTGGCTTCCAGCGCTGTGACGACAAATACTGCGCCGGGTCGTTTTCGCCGCAATATGCCTGCCCCGATC
CCGGTTGTGGTACTGGGTCGTCTGGCGGTGGATAAATCACTACATGGGAAAGGTGTCGGGCGGGCCCTGGTACGTGATGC
CGGGCTGCGTGTGATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTTCACGCCCTGTCGGATGAAGCACGGG
ATTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGAGGGATTTGGTTAAT
GCCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9873.19 Da        Isoelectric Point: 4.4056

>AT177346 WP_193020927.1 NZ_CP062946:2331426-2331692 [Thalassotalea sp. LPB0316]
MKTEMVRARVSSELKHESEAILSELGMSMSDAIRIFLSQVKLRHEFPVELKVPNQDTLKAMEAPVTEDVYDSTDDLFNDI
LGSSSAKD

Download         Length: 267 bp

>AT177346 NZ_CP083445:3359482-3359775 [Klebsiella pneumoniae]
ATGCCAGCCGCAAACAGCATGTCCATAAAACGCGAAACGTTAAATCTGCGCATTAAACCTGCCGAACGCGATCTTATTGA
TCGGGCGGCGAAAGCCAGAGGGAAAAACCGCACAGACTTTGTGCTGGAGGCCGCCCGCGCTGCCGCTGAGGAAGCGCTGA
TTGAGCAACGCATCATTATGGCCGATCCGCAGGCTTATCAGGAATTTCTCGCTCGTCTGGATCAGGCTCCTGCACCTAAT
GCCGCACTGCGTAAAACTATGCAGACCCCTGCGCCGTGGGAACAGGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References