Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 2182039..2182541 Replicon chromosome
Accession NZ_CP062946
Organism Thalassotalea sp. LPB0316

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP316_RS09670 Protein ID WP_193020784.1
Coordinates 2182287..2182541 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP316_RS09665 Protein ID WP_193020783.1
Coordinates 2182039..2182290 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP316_RS09650 2178024..2178980 + 957 WP_193020780.1 acetyl-CoA carboxylase carboxyl transferase subunit alpha -
LP316_RS09655 2179174..2180544 + 1371 WP_193020781.1 tRNA lysidine(34) synthetase TilS -
LP316_RS09660 2180579..2181745 + 1167 WP_193020782.1 dicarboxylate/amino acid:cation symporter -
LP316_RS09665 2182039..2182290 + 252 WP_193020783.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP316_RS09670 2182287..2182541 + 255 WP_193020784.1 Txe/YoeB family addiction module toxin Toxin
LP316_RS09675 2182743..2183204 + 462 WP_193020785.1 hypothetical protein -
LP316_RS09680 2183350..2184687 + 1338 WP_193020786.1 N-succinylarginine dihydrolase -
LP316_RS09685 2184774..2185616 + 843 WP_193020787.1 polyphosphate kinase 2 -
LP316_RS09690 2185619..2186494 + 876 WP_193020788.1 hypothetical protein -
LP316_RS09695 2186495..2187001 + 507 WP_193020789.1 GAF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10062.65 Da        Isoelectric Point: 10.1737

>T177345 WP_193020784.1 NZ_CP062946:2182287-2182541 [Thalassotalea sp. LPB0316]
VKLIFSTNAWQEYLYWQSTDKKILKRINALIKDIQREPHAGIGKPEPLKHGLSGYWSRRINDEHRIVYKLKDDAILIAQL
RYHY

Download         Length: 255 bp

>T177345 NZ_CP083445:2980733-2981080 [Klebsiella pneumoniae]
ATGTGGGATGTAGAAACGACGGATACGTTTGATACCTGGTTCGAATTACAAAGTAGAGCTTTAAAAGAGGATATGTTGGC
CACGATGCTCATCCTGTCTGAGTTTGCTCCGCAGCTTGGGCGCCCGTATGTTGATACGGTGAAAGATTCAACGTTTCAGA
ATATGAAAGAACTGCGGGTTCAGCATCATGGGCTCCCCATCCGCGCCTTTTTTGCTTTTGATCCTCTGCGGAAAGCTATC
GTTTTATGTGCGGGCAATAAGGATGGCATGAATGAGAAACGTTTTTACAAAGAGATGATTACTCTGGCTGACAGAGAATT
CAGCCAACACCTGACTAAGGAGCGATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9246.49 Da        Isoelectric Point: 4.2590

>AT177345 WP_193020783.1 NZ_CP062946:2182039-2182290 [Thalassotalea sp. LPB0316]
MEAISYTAARANLAKTMEKVCDDHSPIIITRKSESPVVMMSLEDYQAMQETTYLLRSPANARALLESIAELEAGNGEERE
LIE

Download         Length: 252 bp

>AT177345 NZ_CP083445:2981080-2981379 [Klebsiella pneumoniae]
ATGGCCACGCTAAAAGAACTCATGGCGAAACAGAGTCCTGATAGCCAGCAGCGTATTGCAGCGAAAGCGGCAGAGATACG
CCAGTCTGTCGCTTTAAACTTGCTTCGAGAAGAGTTGCAAATGTCGCAAACAGAGATGGCTGCGGCTATGGGGGTAAAGC
AGCCAACGATCGCTAAAATGGAACAGGCTGATAACGACCCTCGGCTTTCGACCCTAAAACGCTACATTGCGGCATGGGGG
GGAGAACTCAGTATAAATGTCACATTGCCGACTGGAAAAAAAGTCTCGTTTAATTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References