Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 2839256..2840157 Replicon chromosome
Accession NZ_CP062916
Organism Raoultella terrigena strain Res13-Abat-PEB01-P1-04-A

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag IMO34_RS13465 Protein ID WP_115192781.1
Coordinates 2839696..2840157 (+) Length 154 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag IMO34_RS13460 Protein ID WP_076947124.1
Coordinates 2839256..2839699 (+) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IMO34_RS13440 2835280..2836179 - 900 WP_148249905.1 LysR family transcriptional regulator -
IMO34_RS13445 2836447..2837658 + 1212 WP_195711532.1 SMP-30/gluconolactonase/LRE family protein -
IMO34_RS13450 2837736..2838365 - 630 WP_123552384.1 TetR/AcrR family transcriptional regulator -
IMO34_RS13455 2838403..2839116 + 714 WP_195711534.1 SDR family oxidoreductase -
IMO34_RS13460 2839256..2839699 + 444 WP_076947124.1 DUF2384 domain-containing protein Antitoxin
IMO34_RS13465 2839696..2840157 + 462 WP_115192781.1 RES family NAD+ phosphorylase Toxin
IMO34_RS13470 2840208..2840453 - 246 WP_041145498.1 YmjA family protein -
IMO34_RS13475 2840628..2841119 - 492 WP_045855351.1 GNAT family N-acetyltransferase -
IMO34_RS13480 2841215..2841892 - 678 WP_195711536.1 transporter substrate-binding domain-containing protein -
IMO34_RS13485 2842138..2842653 + 516 WP_195711634.1 hypothetical protein -
IMO34_RS13490 2842698..2843981 - 1284 WP_041145496.1 citrate synthase -
IMO34_RS13495 2844155..2844871 - 717 WP_041145495.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - mgtB 2665918..2921949 256031


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-147)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(32-89)


Sequences

Toxin        


Download         Length: 154 a.a.        Molecular weight: 16811.16 Da        Isoelectric Point: 5.1554

>T177318 WP_115192781.1 NZ_CP062916:2839696-2840157 [Raoultella terrigena]
VILYRLTKSRFLTTAWSGFGAKEAGGRWNSVGTAMVYLSEAASLTMLETLVHINAPQLLDDFTLLSIDVPDDQVLTVDPA
SLPADWAREDAPARLARYGDEWAASAASAALRVPSALSPVEYNYLFNPQHPAVFDLLASVKRIPFRFDTRLKA

Download         Length: 462 bp

>T177318 NZ_CP083442:c3210309-3210127 [Pseudomonas chlororaphis]
ATGCGCAGTCGGGAACTGATCAGGATGATCGAGGAGGACGGGTGGTATCTGATCGCGGTCAAAGGCAGTCATCACCAGTA
CAAACATCTGCACAAGCCGGGGCGGGTCACTATCCCTCACCCGGATGCGGATCTGCCCAGGGGCACGATCCACAGCATCT
TGAAACAGGCGGGCCTGAAATGA

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16367.62 Da        Isoelectric Point: 6.7345

>AT177318 WP_076947124.1 NZ_CP062916:2839256-2839699 [Raoultella terrigena]
MKVYSPTENTEKNLSPWHAIGLDAEDGIALMGKISHGLEGSVARQISAWAEITPAELRKMSGIANTTFNRSIKSRFSADQ
SERLVRILRVIERAVELFEGDKEAAQKWMNEPNRALGWKTPAEVVSSETGALEVMRLITRVEHGVYS

Download         Length: 444 bp

>AT177318 NZ_CP083442:c3210097-3209696 [Pseudomonas chlororaphis]
ATGAAATTCCCGGTCGTGCTGCACAAGGATGCCGACTCCGGATATGGAGTGATCGTCCCCGATGTGCCGGGCTGTTTTTC
CGCCGGTCATACCGCTGCGCAAGCCTTCGAGAATGTGAAAGAAGCCTTGTCGCTGCACTACGAAGGCCTGGTCGCCGATG
GTGAGCCGCTGCCCCAGGTACATGAGGTTGATGTGCATATCGACAATCCCGATTACGCCGGCGGTGTATGGGGGGTGGTC
GATTTCGATATCACGCCTTACTTCGGCAAGGCGGTGCGTTTTAATGCGACGTTGCCGGAGCAACTGTTGGAGCGCATCGA
CCAGACAGTGAAGCGCGACCAGCGCTACCGTTCGCGCTCGGGTTTTCTCGCCGCGGCGGCACTACGCGAGCTCTCCGCCT
AG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References