Detailed information of TA system TA176708

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): sanaTA/AbiEii-DUF6088
• Location: 4527303..4528659
• Replicon: chromosome
• Accession: NZ_CP062821
• Organism: Providencia rettgeri strain Res13-Sevr-LER2-35

Toxin (Protein)

• Gene name: sanaT
• Uniprot ID: -
• Locus tag: IMQ36_RS21110
• Protein ID: WP_102140047.1
• Coordinates: 4527694..4528659 (+)
• Length: 322 a.a.

Antitoxin (Protein)

• Gene name: sanaA
• Uniprot ID: -
• Locus tag: IMQ36_RS21105
• Protein ID: WP_102140046.1
• Coordinates: 4527303..4527707 (+)
• Length: 135 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IMQ36_RS21095	4523089..4526136	-	3048	WP_195697953.1	formate dehydrogenase-N subunit alpha	-
IMQ36_RS21100	4526311..4527141	+	831	WP_102140045.1	formate dehydrogenase accessory sulfurtransferase FdhD	-
IMQ36_RS21105	4527303..4527707	+	405	WP_102140046.1	S-adenosylhomocysteine hydrolase	Antitoxin
IMQ36_RS21110	4527694..4528659	+	966	WP_102140047.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
IMQ36_RS21115	4528731..4530095	-	1365	WP_195697954.1	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE	-
IMQ36_RS21120	4530196..4531845	-	1650	WP_004906225.1	membrane protein insertase YidC	-
IMQ36_RS21125	4531848..4532108	-	261	WP_102140049.1	membrane protein insertion efficiency factor YidD	-
IMQ36_RS21130	4532072..4532431	-	360	WP_102140050.1	ribonuclease P protein component	-
IMQ36_RS21135	4532453..4532596	-	144	WP_042846776.1	50S ribosomal protein L34	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (39-300)

Antitoxin

• Protein of unknown function DUF6088 (6-131)

Sequences

Toxin

Protein

• Length: 322 a.a.
• Molecular weight: 37124.16 Da
• Isoelectric Point: 5.0044

>T176708 WP_102140047.1 NZ_CP062821:4527694-4528659 [Providencia rettgeri]
MKLDSSLFIDVADAIGLGNPAIVEKDYYVVQLLKLLSNFQFTYHQAIFSGGTALAKSDIKTYRMSEDIDIKLIPNQRYSE
LASRNARKTARREIKNIIEEIINQNSIFSLDNAPSVKDEYRYFSFDIRYPQDHRQAPCLRPFIKLEFIETDLLSEPISRN
IQSIYSNVTESDIEIYNMICSAIIDTQAEKLLSMLRRTASVARNGQREDDETLIRHVYDTFHIQLSQPSNIEFLSQLLKK
ALDGDITRYGNQHTQLVDSPITELRYGLKLLVETPKFIERYNNYVSPMVYAEVPTQWDEAIIAFTSLAHQVLDYIEQELN
K

Nucleotide

• Length: 966 bp

>T176708 NZ_CP082909:c5238336-5237920 [Endozoicomonas sp. 4G]
ATGATATTACTCGACACCAATATTATTTCGGAAACCATGAGGCAGTCACCCGATACGGCTGTCGTTGGTTGGCTGAATGA
ACAAATAAGTGAAACGCTCTACCTGTCCAGTGTGACGCTGGCCGAATTGCTGTTTGGCATTCTGGCTTTGCCTGACGGTC
GTCGGAAGCAGCAATTGAGCCAGGCTGTGGATCAATACACCACTCTTTTCAGGGGCCGCATTCTGGAATTTGATGTGGCC
GCTGCCAGAGAATACGCAGAGTTGGCAGTGCTGGCCAGAAAAAGGGGACGGGGCTTTCCAGTGCCTGATGGCTATATTGC
CGCCATTGCTTCCGTGCACGGATTCCGGGTTGCTTCCCGAGATGTTGCACCGTTCGAAGCCGCTAACGTCCCTGTAGTTA
ACCCATGGTTGGATTAA

Antitoxin

Protein

• Length: 135 a.a.
• Molecular weight: 15286.99 Da
• Isoelectric Point: 11.0636

>AT176708 WP_102140046.1 NZ_CP062821:4527303-4527707 [Providencia rettgeri]
MTIQDRIQKKVKRSKRSVFLRSDFSKIADYDQVGRILKKLTDNGLLMRIGYGVYVRARVNRITGKLMPDNPSGADGVIIE
VMKKLNVDYTFDKLSLMNLSGESTQIPSNIKIIPKNPKFTRKIKVGKQSINETR

Nucleotide

• Length: 405 bp

>AT176708 NZ_CP082909:c5238588-5238337 [Endozoicomonas sp. 4G]
ATGGCAATGATGACCCTTAGAAATATCCCAGATGAGCTGTACAGTGCCCTTAAGGTCAGGGCTAAACGAAATAACCGCAG
CATGGTTGCCGAGGTTCGGAATATTCTCAGAGAGGTTTTACAACCTGAGGATCGGGTGTTGATGGGTGATGCTCTGGTTA
ATGCCGGACAGGACATCGGCCTGACGGATGAAGAAGTTGATATTCTGGAGCAAAACCGGGATAAGACGCCAGCGGAACCG
GTGAAATTTTGA