Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 911727..912373 Replicon chromosome
Accession NZ_CP062821
Organism Providencia rettgeri strain Res13-Sevr-LER2-35

Toxin (Protein)


Gene name Hha Uniprot ID -
Locus tag IMQ36_RS03895 Protein ID WP_102139052.1
Coordinates 911727..911930 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag IMQ36_RS03900 Protein ID WP_102139053.1
Coordinates 912005..912373 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IMQ36_RS03870 907825..908163 + 339 WP_004905421.1 P-II family nitrogen regulator -
IMQ36_RS03875 908213..909460 + 1248 WP_181490144.1 ammonium transporter AmtB -
IMQ36_RS03880 909600..910469 - 870 WP_166266727.1 acyl-CoA thioesterase II -
IMQ36_RS03885 910709..911167 + 459 WP_102139051.1 YbaY family lipoprotein -
IMQ36_RS03895 911727..911930 - 204 WP_102139052.1 hemolysin expression modulator Hha Toxin
IMQ36_RS03900 912005..912373 - 369 WP_102139053.1 Hha toxicity modulator TomB Antitoxin
IMQ36_RS03905 912902..914272 - 1371 WP_102139054.1 murein transglycosylase D -
IMQ36_RS03910 914354..915109 - 756 WP_195698223.1 hydroxyacylglutathione hydrolase -
IMQ36_RS03915 915150..915884 + 735 WP_195698224.1 methyltransferase domain-containing protein -
IMQ36_RS03920 915881..916351 - 471 WP_102139057.1 ribonuclease HI -
IMQ36_RS03925 916406..917167 + 762 WP_102139069.1 DNA polymerase III subunit epsilon -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-117)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8121.44 Da        Isoelectric Point: 6.9770

>T176701 WP_102139052.1 NZ_CP062821:c911930-911727 [Providencia rettgeri]
MTKFDYLMRLRKCTTIETLERVIEKNKYELSDDELELFYSAADHRLAELTMNKLYDKIPASVWKFVR

Download         Length: 204 bp

>T176701 NZ_CP082909:3602541-3602810 [Endozoicomonas sp. 4G]
ATGCTTACTCCAGTACGATCAACGAAGTTTAAAAAGGATTACAAGAAAGTCGAACGGCAAGGTAAGGATTTAAAGAAACT
TAAAACGATTATGGTTCGGCTTGCCAAAGAAGAAATCCTTGAACCTAAGTATAAAGATCACTACCTGACCGGAAACTACA
AAGGGCGTAGAGAATGTCATATAGAGCCTGACTGGTTATTGATCTACATGATTGTTGGGAGTGAAATCTTTTTTGAAAGA
ACTGGATCACATTCTGAATTATTTAGGTAG

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14033.99 Da        Isoelectric Point: 4.3849

>AT176701 WP_102139053.1 NZ_CP062821:c912373-912005 [Providencia rettgeri]
MDEYSPKKHDIAELKYLCNSLNRDAILSLQKTNTHWINDLSSPQSAALNELIEHIAAFVWRFKIKYPKENLVISLIEEYL
DETYDLFGSPVITLSEVIDWEAMNQSLVAVLDDDLKCLTSKT

Download         Length: 369 bp

>AT176701 NZ_CP082909:3602278-3602541 [Endozoicomonas sp. 4G]
ATGAGCAAGAGCGCAATGATCCGAGCCAGAATAGAACCTGATGTAAAGGAACATGCAGAAGCGATATTCAGGAAACTCGG
ACTTAACGCAACAGACGCAATCACTTTGTTTTATAAGCAGGTAGGCTTGTGTAACGGATTGCCCTTTGATGTTCGTATAC
CTAATGAAGAAACCCTGAAAGCCTTCAAGGATACAGACAAAGGGGTAGGCTTAACTCATTACGATTCAATGGAAGAAATG
TTTGATGATCTGGATGCTGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References