Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1938158..1938303 Replicon chromosome
Accession NZ_CP062792
Organism Klebsiella pneumoniae strain 33Kpn12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1938194..1938296 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1938158..1938303 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IFY65_RS09520 1933288..1935348 + 2061 WP_032420218.1 oligopeptidase B -
IFY65_RS09525 1935352..1936011 - 660 WP_002911407.1 exodeoxyribonuclease X -
IFY65_RS09530 1936090..1936320 - 231 WP_002911406.1 DNA polymerase III subunit theta -
IFY65_RS09535 1936433..1936807 + 375 WP_004151448.1 CopC domain-containing protein YobA -
IFY65_RS09540 1936811..1937680 + 870 WP_032420215.1 copper homeostasis membrane protein CopD -
IFY65_RS09545 1937697..1938035 + 339 WP_002911404.1 YebY family protein -
- 1938158..1938303 - 146 - - Antitoxin
- 1938194..1938296 + 103 - - Toxin
IFY65_RS09550 1938671..1938814 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
IFY65_RS09555 1938919..1939887 - 969 WP_004151446.1 VirK/YbjX family protein -
IFY65_RS09560 1940044..1940697 + 654 WP_016529030.1 protein-serine/threonine phosphatase -
IFY65_RS09565 1940694..1940885 - 192 WP_002911395.1 YebW family protein -
IFY65_RS09570 1940983..1941222 - 240 WP_002911393.1 YebV family protein -
IFY65_RS09575 1941338..1942771 - 1434 WP_064149175.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T176608 NZ_CP062792:1938194-1938296 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT176608 NZ_CP062792:c1938303-1938158 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References