Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2327910..2328181 Replicon chromosome
Accession NZ_CP062778
Organism Escherichia coli O157:H7 strain Z1836

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2328040..2328143 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2327910..2328181 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ILQ64_RS11760 2324465..2325127 - 663 WP_000944243.1 exodeoxyribonuclease X -
ILQ64_RS11765 2325151..2325807 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
ILQ64_RS11770 2325909..2326139 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ILQ64_RS11775 2326278..2326652 + 375 WP_000168751.1 CopC domain-containing protein YobA -
ILQ64_RS11780 2326656..2327528 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
ILQ64_RS11785 2327541..2327882 + 342 WP_000976483.1 YebY family protein -
- 2327910..2328181 - 272 - - Antitoxin
- 2328040..2328143 + 104 - - Toxin
ILQ64_RS11790 2328278..2328934 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
ILQ64_RS11795 2328935..2329126 - 192 WP_001296140.1 YebW family protein -
ILQ64_RS11800 2329231..2329467 - 237 WP_001295499.1 DUF1480 family protein -
ILQ64_RS11805 2329585..2331024 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T176498 NZ_CP062778:2328040-2328143 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT176498 NZ_CP062778:c2328181-2327910 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References