Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2314285..2314556 Replicon chromosome
Accession NZ_CP062771
Organism Escherichia coli O157:H7 strain Z570

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2314415..2314518 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2314285..2314556 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ILQ32_RS11655 2310840..2311502 - 663 WP_000944243.1 exodeoxyribonuclease X -
ILQ32_RS11660 2311526..2312182 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
ILQ32_RS11665 2312284..2312514 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ILQ32_RS11670 2312653..2313027 + 375 WP_000168751.1 CopC domain-containing protein YobA -
ILQ32_RS11675 2313031..2313903 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
ILQ32_RS11680 2313916..2314257 + 342 WP_000976483.1 YebY family protein -
- 2314285..2314556 - 272 - - Antitoxin
- 2314415..2314518 + 104 - - Toxin
ILQ32_RS11685 2314653..2315309 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
ILQ32_RS11690 2315310..2315501 - 192 WP_001296140.1 YebW family protein -
ILQ32_RS11695 2315606..2315842 - 237 WP_001295499.1 DUF1480 family protein -
ILQ32_RS11700 2315960..2317399 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T176422 NZ_CP062771:2314415-2314518 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT176422 NZ_CP062771:c2314556-2314285 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References