Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2358494..2358765 Replicon chromosome
Accession NZ_CP062766
Organism Escherichia coli O157:H7 strain Z866

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2358624..2358727 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2358494..2358765 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ILQ34_RS11920 2355049..2355711 - 663 WP_000944243.1 exodeoxyribonuclease X -
ILQ34_RS11925 2355735..2356391 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
ILQ34_RS11930 2356493..2356723 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ILQ34_RS11935 2356862..2357236 + 375 WP_000168751.1 CopC domain-containing protein YobA -
ILQ34_RS11940 2357240..2358112 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
ILQ34_RS11945 2358125..2358466 + 342 WP_000976483.1 YebY family protein -
- 2358494..2358765 - 272 - - Antitoxin
- 2358624..2358727 + 104 - - Toxin
ILQ34_RS11950 2358862..2359518 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
ILQ34_RS11955 2359519..2359710 - 192 WP_001296140.1 YebW family protein -
ILQ34_RS11960 2359815..2360051 - 237 WP_001295499.1 DUF1480 family protein -
ILQ34_RS11965 2360169..2361608 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T176355 NZ_CP062766:2358624-2358727 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT176355 NZ_CP062766:c2358765-2358494 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References