Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2294513..2294784 Replicon chromosome
Accession NZ_CP062761
Organism Escherichia coli O157:H7 strain Z887

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2294643..2294746 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2294513..2294784 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ILQ37_RS11490 2291068..2291730 - 663 WP_000944243.1 exodeoxyribonuclease X -
ILQ37_RS11495 2291754..2292410 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
ILQ37_RS11500 2292512..2292742 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ILQ37_RS11505 2292881..2293255 + 375 WP_000168751.1 CopC domain-containing protein YobA -
ILQ37_RS11510 2293259..2294131 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
ILQ37_RS11515 2294144..2294485 + 342 WP_000976483.1 YebY family protein -
- 2294513..2294784 - 272 - - Antitoxin
- 2294643..2294746 + 104 - - Toxin
ILQ37_RS11520 2294881..2295537 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
ILQ37_RS11525 2295538..2295729 - 192 WP_001296140.1 YebW family protein -
ILQ37_RS11530 2295834..2296070 - 237 WP_001295499.1 DUF1480 family protein -
ILQ37_RS11535 2296188..2297627 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T176279 NZ_CP062761:2294643-2294746 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT176279 NZ_CP062761:c2294784-2294513 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References