Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2304724..2304995 Replicon chromosome
Accession NZ_CP062758
Organism Escherichia coli O157:H7 strain Z892

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2304854..2304957 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2304724..2304995 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ILQ38_RS11600 2301279..2301941 - 663 WP_000944243.1 exodeoxyribonuclease X -
ILQ38_RS11605 2301965..2302621 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
ILQ38_RS11610 2302723..2302953 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ILQ38_RS11615 2303092..2303466 + 375 WP_000168751.1 CopC domain-containing protein YobA -
ILQ38_RS11620 2303470..2304342 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
ILQ38_RS11625 2304355..2304696 + 342 WP_000976483.1 YebY family protein -
- 2304724..2304995 - 272 - - Antitoxin
- 2304854..2304957 + 104 - - Toxin
ILQ38_RS11630 2305092..2305748 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
ILQ38_RS11635 2305749..2305940 - 192 WP_001296140.1 YebW family protein -
ILQ38_RS11640 2306045..2306281 - 237 WP_001295499.1 DUF1480 family protein -
ILQ38_RS11645 2306399..2307838 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T176243 NZ_CP062758:2304854-2304957 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT176243 NZ_CP062758:c2304995-2304724 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References