Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3006110..3006381 Replicon chromosome
Accession NZ_CP062755
Organism Escherichia coli O157:H7 strain Z903

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3006148..3006251 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3006110..3006381 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ILQ39_RS15185 3003267..3004706 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ILQ39_RS15190 3004824..3005060 + 237 WP_001295499.1 DUF1480 family protein -
ILQ39_RS15195 3005165..3005356 + 192 WP_001296140.1 YebW family protein -
ILQ39_RS15200 3005357..3006013 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 3006110..3006381 + 272 - - Antitoxin
- 3006148..3006251 - 104 - - Toxin
ILQ39_RS15205 3006409..3006750 - 342 WP_000976483.1 YebY family protein -
ILQ39_RS15210 3006763..3007635 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
ILQ39_RS15215 3007639..3008013 - 375 WP_000168751.1 CopC domain-containing protein YobA -
ILQ39_RS15220 3008152..3008382 + 231 WP_000916763.1 DNA polymerase III subunit theta -
ILQ39_RS15225 3008484..3009140 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
ILQ39_RS15230 3009164..3009826 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T176211 NZ_CP062755:c3006251-3006148 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT176211 NZ_CP062755:3006110-3006381 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References