Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3392955..3393226 Replicon chromosome
Accession NZ_CP062746
Organism Escherichia coli O157:H7 strain Z1504

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3392993..3393096 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3392955..3393226 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ILQ42_RS17295 3390112..3391551 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ILQ42_RS17300 3391669..3391905 + 237 WP_001295499.1 DUF1480 family protein -
ILQ42_RS17305 3392010..3392201 + 192 WP_001296140.1 YebW family protein -
ILQ42_RS17310 3392202..3392858 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 3392955..3393226 + 272 - - Antitoxin
- 3392993..3393096 - 104 - - Toxin
ILQ42_RS17315 3393254..3393595 - 342 WP_000976483.1 YebY family protein -
ILQ42_RS17320 3393608..3394480 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
ILQ42_RS17325 3394484..3394858 - 375 WP_000168751.1 CopC domain-containing protein YobA -
ILQ42_RS17330 3394997..3395227 + 231 WP_000916763.1 DNA polymerase III subunit theta -
ILQ42_RS17335 3395329..3395985 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
ILQ42_RS17340 3396009..3396671 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T176104 NZ_CP062746:c3393096-3392993 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT176104 NZ_CP062746:3392955-3393226 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References