Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2528813..2529084 Replicon chromosome
Accession NZ_CP062739
Organism Escherichia coli O157:H7 strain Z1723

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2528943..2529046 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2528813..2529084 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ILQ45_RS12895 2525368..2526030 - 663 WP_000944243.1 exodeoxyribonuclease X -
ILQ45_RS12900 2526054..2526710 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
ILQ45_RS12905 2526812..2527042 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ILQ45_RS12910 2527181..2527555 + 375 WP_000168751.1 CopC domain-containing protein YobA -
ILQ45_RS12915 2527559..2528431 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
ILQ45_RS12920 2528444..2528785 + 342 WP_000976483.1 YebY family protein -
- 2528813..2529084 - 272 - - Antitoxin
- 2528943..2529046 + 104 - - Toxin
ILQ45_RS12925 2529181..2529837 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
ILQ45_RS12930 2529838..2530029 - 192 WP_001296140.1 YebW family protein -
ILQ45_RS12935 2530134..2530370 - 237 WP_001295499.1 DUF1480 family protein -
ILQ45_RS12940 2530488..2531927 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T175987 NZ_CP062739:2528943-2529046 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT175987 NZ_CP062739:c2529084-2528813 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References