Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2364550..2364821 Replicon chromosome
Accession NZ_CP062711
Organism Escherichia coli O157:H7 strain Z1831

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2364680..2364783 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2364550..2364821 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ILQ59_RS11955 2361105..2361767 - 663 WP_000944243.1 exodeoxyribonuclease X -
ILQ59_RS11960 2361791..2362447 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
ILQ59_RS11965 2362549..2362779 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ILQ59_RS11970 2362918..2363292 + 375 WP_000168751.1 CopC domain-containing protein YobA -
ILQ59_RS11975 2363296..2364168 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
ILQ59_RS11980 2364181..2364522 + 342 WP_000976483.1 YebY family protein -
- 2364550..2364821 - 272 - - Antitoxin
- 2364680..2364783 + 104 - - Toxin
ILQ59_RS11985 2364918..2365574 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
ILQ59_RS11990 2365575..2365766 - 192 WP_001296140.1 YebW family protein -
ILQ59_RS11995 2365871..2366107 - 237 WP_001295499.1 DUF1480 family protein -
ILQ59_RS12000 2366225..2367664 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T175515 NZ_CP062711:2364680-2364783 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT175515 NZ_CP062711:c2364821-2364550 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References