Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2364539..2364810 Replicon chromosome
Accession NZ_CP062708
Organism Escherichia coli O157:H7 strain Z1832

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2364669..2364772 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2364539..2364810 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ILQ60_RS11955 2361094..2361756 - 663 WP_000944243.1 exodeoxyribonuclease X -
ILQ60_RS11960 2361780..2362436 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
ILQ60_RS11965 2362538..2362768 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ILQ60_RS11970 2362907..2363281 + 375 WP_000168751.1 CopC domain-containing protein YobA -
ILQ60_RS11975 2363285..2364157 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
ILQ60_RS11980 2364170..2364511 + 342 WP_000976483.1 YebY family protein -
- 2364539..2364810 - 272 - - Antitoxin
- 2364669..2364772 + 104 - - Toxin
ILQ60_RS11985 2364907..2365563 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
ILQ60_RS11990 2365564..2365755 - 192 WP_001296140.1 YebW family protein -
ILQ60_RS11995 2365860..2366096 - 237 WP_001295499.1 DUF1480 family protein -
ILQ60_RS12000 2366214..2367653 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T175477 NZ_CP062708:2364669-2364772 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT175477 NZ_CP062708:c2364810-2364539 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References