Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2364543..2364814 Replicon chromosome
Accession NZ_CP062705
Organism Escherichia coli O157:H7 strain Z1833

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2364673..2364776 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2364543..2364814 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ILQ61_RS11955 2361098..2361760 - 663 WP_000944243.1 exodeoxyribonuclease X -
ILQ61_RS11960 2361784..2362440 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
ILQ61_RS11965 2362542..2362772 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ILQ61_RS11970 2362911..2363285 + 375 WP_000168751.1 CopC domain-containing protein YobA -
ILQ61_RS11975 2363289..2364161 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
ILQ61_RS11980 2364174..2364515 + 342 WP_000976483.1 YebY family protein -
- 2364543..2364814 - 272 - - Antitoxin
- 2364673..2364776 + 104 - - Toxin
ILQ61_RS11985 2364911..2365567 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
ILQ61_RS11990 2365568..2365759 - 192 WP_001296140.1 YebW family protein -
ILQ61_RS11995 2365864..2366100 - 237 WP_001295499.1 DUF1480 family protein -
ILQ61_RS12000 2366218..2367657 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T175439 NZ_CP062705:2364673-2364776 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT175439 NZ_CP062705:c2364814-2364543 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References