Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2288784..2289055 Replicon chromosome
Accession NZ_CP062702
Organism Escherichia coli O157:H7 strain Z1834

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2288914..2289017 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2288784..2289055 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ILQ62_RS11430 2285339..2286001 - 663 WP_000944243.1 exodeoxyribonuclease X -
ILQ62_RS11435 2286025..2286681 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
ILQ62_RS11440 2286783..2287013 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ILQ62_RS11445 2287152..2287526 + 375 WP_000168751.1 CopC domain-containing protein YobA -
ILQ62_RS11450 2287530..2288402 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
ILQ62_RS11455 2288415..2288756 + 342 WP_000976483.1 YebY family protein -
- 2288784..2289055 - 272 - - Antitoxin
- 2288914..2289017 + 104 - - Toxin
ILQ62_RS11460 2289152..2289808 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
ILQ62_RS11465 2289809..2290000 - 192 WP_001296140.1 YebW family protein -
ILQ62_RS11470 2290105..2290341 - 237 WP_001295499.1 DUF1480 family protein -
ILQ62_RS11475 2290459..2291898 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T175401 NZ_CP062702:2288914-2289017 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT175401 NZ_CP062702:c2289055-2288784 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References