Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2280372..2280643 Replicon chromosome
Accession NZ_CP062700
Organism Escherichia coli O157:H7 strain Z1835

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2280502..2280605 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2280372..2280643 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ILQ63_RS11455 2276927..2277589 - 663 WP_000944243.1 exodeoxyribonuclease X -
ILQ63_RS11460 2277613..2278269 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
ILQ63_RS11465 2278371..2278601 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ILQ63_RS11470 2278740..2279114 + 375 WP_000168751.1 CopC domain-containing protein YobA -
ILQ63_RS11475 2279118..2279990 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
ILQ63_RS11480 2280003..2280344 + 342 WP_000976483.1 YebY family protein -
- 2280372..2280643 - 272 - - Antitoxin
- 2280502..2280605 + 104 - - Toxin
ILQ63_RS11485 2280740..2281396 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
ILQ63_RS11490 2281397..2281588 - 192 WP_001296140.1 YebW family protein -
ILQ63_RS11495 2281693..2281929 - 237 WP_001295499.1 DUF1480 family protein -
ILQ63_RS11500 2282047..2283486 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T175364 NZ_CP062700:2280502-2280605 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT175364 NZ_CP062700:c2280643-2280372 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References