Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 2531998..2532551 Replicon chromosome
Accession NZ_CP062698
Organism Anthocerotibacter panamensis C109

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag IL331_RS11935 Protein ID WP_218079614.1
Coordinates 2531998..2532297 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag IL331_RS11940 Protein ID WP_218079615.1
Coordinates 2532297..2532551 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IL331_RS11905 2527221..2528192 + 972 WP_218079610.1 hydroxymethylbilane synthase -
IL331_RS11910 2528342..2528680 + 339 WP_245395450.1 four-helix bundle copper-binding protein -
IL331_RS11915 2528792..2529421 - 630 WP_218079611.1 phycobiliprotein lyase -
IL331_RS11925 2529982..2531712 + 1731 WP_218079612.1 iron uptake porin -
IL331_RS11930 2531800..2531994 + 195 WP_218079613.1 hypothetical protein -
IL331_RS11935 2531998..2532297 - 300 WP_218079614.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IL331_RS11940 2532297..2532551 - 255 WP_218079615.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
IL331_RS11945 2533000..2533593 + 594 WP_218079616.1 chorismate lyase -
IL331_RS11950 2533624..2535834 + 2211 WP_218079617.1 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase -
IL331_RS11955 2535921..2536133 + 213 WP_218079618.1 hypothetical protein -
IL331_RS11960 2536158..2536646 + 489 WP_218079619.1 hypothetical protein -
IL331_RS11965 2536657..2537148 + 492 WP_218079620.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-91)

Antitoxin

Antitoxin ParD

(1-76)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11881.36 Da        Isoelectric Point: 8.4497

>T175349 WP_218079614.1 NZ_CP062698:c2532297-2531998 [Anthocerotibacter panamensis C109]
MGVFRLTELAKADLRAIGRYTQQTWGRDQRNSYLARLDKSFQRLAEEPERGRPYDEIRAGYRKYHVGRHLIFYREAQDSI
EIVRILHDRMDIETHLSDD

Download         Length: 300 bp

>T175349 NZ_CP081891:4034202-4034420 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9285.43 Da        Isoelectric Point: 4.4545

>AT175349 WP_218079615.1 NZ_CP062698:c2532551-2532297 [Anthocerotibacter panamensis C109]
MQKNTSVTLGEHFETFIAVQIQAGRFASASEVIRAGLRLLEEQEMKVQALRRALQEGEESGLAEYSLQGLLHELDAVAPS
QEQT

Download         Length: 255 bp

>AT175349 NZ_CP081891:4033801-4034175 [Klebsiella pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References