Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 1358988..1359490 Replicon chromosome
Accession NZ_CP062698
Organism Anthocerotibacter panamensis C109

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag IL331_RS06290 Protein ID WP_218082264.1
Coordinates 1359236..1359490 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IL331_RS06285 Protein ID WP_218082263.1
Coordinates 1358988..1359239 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IL331_RS06255 1354599..1355393 + 795 WP_218082257.1 ABC transporter permease -
IL331_RS06260 1355390..1355890 - 501 WP_218082258.1 hypothetical protein -
IL331_RS06265 1355944..1356861 - 918 WP_218082259.1 DUF1338 domain-containing protein -
IL331_RS06270 1357075..1357446 + 372 WP_218082260.1 hypothetical protein -
IL331_RS06275 1357626..1358111 + 486 WP_218082261.1 Hsp20/alpha crystallin family protein -
IL331_RS06280 1358176..1358850 + 675 WP_218082262.1 phosphoribosyltransferase -
IL331_RS06285 1358988..1359239 + 252 WP_218082263.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
IL331_RS06290 1359236..1359490 + 255 WP_218082264.1 Txe/YoeB family addiction module toxin Toxin
IL331_RS06295 1359829..1360992 - 1164 WP_218082265.1 sulfate adenylyltransferase -
IL331_RS06300 1361101..1361649 - 549 WP_218082266.1 ribosome recycling factor -
IL331_RS06305 1361818..1362141 + 324 WP_218082267.1 hypothetical protein -
IL331_RS06310 1362269..1362466 + 198 WP_218082268.1 DUF2795 domain-containing protein -
IL331_RS06315 1362646..1363332 + 687 WP_218082269.1 pirin family protein -
IL331_RS06320 1363335..1364030 - 696 WP_218082270.1 DUF1995 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10179.79 Da        Isoelectric Point: 9.3762

>T175348 WP_218082264.1 NZ_CP062698:1359236-1359490 [Anthocerotibacter panamensis C109]
VKLIFAEQSWEDYLHWQQLDKRIVKRINELIEATMRDPFVGIGKPEPLKHALAGYWSRRITEEHRMVYKAERDALLIAQL
RYHY

Download         Length: 255 bp

>T175348 NZ_CP081891:c3883043-3882726 [Klebsiella pneumoniae]
ATGTTCAGATTGGTTGTGCATGTGGACGTTAAAAAGGAATTGCAGGCGCTTCCGTCCATTGTCCAGGCGAAGATGATCCG
GCAATTAGACAAGTTACGCCAAAATCCCACCGCGCTGAGAGAACCTGACAGTAAACCGCTGGGGCAGGGGCTATTTGAAA
TTCGTGCGTTAGGTTCGGTACAGGGGCGAGGGATCTACGTTTTTCAGCAAGGCAAGACGCTCTTTCTGCTACGGGTTTTT
GTCAAGAAAACGCAAAAAACCCCGTCATCGGAAATTCGCCTGGCGCTGAAGCGATTAGAGGAAATGCGCAATGAGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9307.64 Da        Isoelectric Point: 5.8425

>AT175348 WP_218082263.1 NZ_CP062698:1358988-1359239 [Anthocerotibacter panamensis C109]
MDAITYSAARANLASTMDKVCEDHEPLIITRNGRQSVVMLSLEDYNALEETVYLLRSPENAKRLLSAVEDLARGRGKEQK
LVK

Download         Length: 252 bp

>AT175348 NZ_CP081891:c3882733-3882446 [Klebsiella pneumoniae]
ATGAGTAAAAAGATCATTGACTGGGATACGTTAAAAACAGAACTGCTTGGCCAGCCTGAGGTTCAGGCTGCATTCGATGC
GCAAGAACGTCAACAGCGATTACGTACTATGCTGGCGCAATGGCGCGAGCAGGCGGGGCTAACCCGAGCCCAGGTGGCGC
AGAGGATGGGGGTGAGTGCGCCGACGGTCTCCAGAATGGAAGCCAATATCACCCGCGCCAGTCTGGATACCTTAACGCGA
TACGCGTTAGCCTGCGGTATAAAGCACCCGCAAGTTTTACTTTACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References