Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | TscAT/- |
| Location | 836169..836701 | Replicon | chromosome |
| Accession | NZ_CP062364 | ||
| Organism | Staphylococcus aureus strain NAS_AN_130 | ||
Toxin (Protein)
| Gene name | TscT | Uniprot ID | - |
| Locus tag | IF714_RS03965 | Protein ID | WP_240017340.1 |
| Coordinates | 836381..836701 (+) | Length | 107 a.a. |
Antitoxin (Protein)
| Gene name | TscA | Uniprot ID | - |
| Locus tag | IF714_RS03960 | Protein ID | WP_001058486.1 |
| Coordinates | 836169..836378 (+) | Length | 70 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IF714_RS03915 (IF714_03915) | 831188..832408 | - | 1221 | WP_000266157.1 | site-specific integrase | - |
| IF714_RS03920 (IF714_03920) | 832497..833225 | - | 729 | WP_000733774.1 | staphylococcal enterotoxin type K | - |
| IF714_RS03925 (IF714_03925) | 833249..833977 | - | 729 | WP_001033316.1 | staphylococcal enterotoxin type Q | - |
| IF714_RS03930 (IF714_03930) | 834047..834478 | - | 432 | WP_001228759.1 | hypothetical protein | - |
| IF714_RS03935 (IF714_03935) | 834495..834953 | - | 459 | WP_000281657.1 | ImmA/IrrE family metallo-endopeptidase | - |
| IF714_RS03940 (IF714_03940) | 834965..835297 | - | 333 | WP_001260004.1 | helix-turn-helix transcriptional regulator | - |
| IF714_RS03945 (IF714_03945) | 835490..835753 | + | 264 | WP_000243850.1 | helix-turn-helix transcriptional regulator | - |
| IF714_RS03950 (IF714_03950) | 835746..836018 | + | 273 | WP_000091731.1 | helix-turn-helix domain-containing protein | - |
| IF714_RS03955 (IF714_03955) | 836030..836176 | + | 147 | WP_000784875.1 | hypothetical protein | - |
| IF714_RS03960 (IF714_03960) | 836169..836378 | + | 210 | WP_001058486.1 | hypothetical protein | Antitoxin |
| IF714_RS03965 (IF714_03965) | 836381..836701 | + | 321 | WP_240017340.1 | DUF1474 family protein | Toxin |
| IF714_RS03970 (IF714_03970) | 836765..837634 | + | 870 | WP_001002732.1 | primase alpha helix C-terminal domain-containing protein | - |
| IF714_RS03975 (IF714_03975) | 837651..839120 | + | 1470 | WP_000390454.1 | virulence-associated E family protein | - |
| IF714_RS03980 (IF714_03980) | 839406..839768 | + | 363 | WP_001039168.1 | hypothetical protein | - |
| IF714_RS03985 (IF714_03985) | 839770..840054 | + | 285 | WP_000998181.1 | hypothetical protein | - |
| IF714_RS03990 (IF714_03990) | 840051..840692 | + | 642 | WP_001019764.1 | hypothetical protein | - |
| IF714_RS03995 (IF714_03995) | 841210..841551 | + | 342 | WP_001190615.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | vWbp / selk / selq / seb | 801138..846502 | 45364 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 107 a.a. Molecular weight: 12713.26 Da Isoelectric Point: 4.7440
>T174618 WP_240017340.1 NZ_CP062364:836381-836701 [Staphylococcus aureus]
MNWEIKDLMCDIEVIKQKINDVATKHAWFVEDRFVKNELETKREHINFSASYLEHRIQNEHTVELLHVYLKEFSELIQKF
REIEKASSENFDEESDDAKNSIKVAE
MNWEIKDLMCDIEVIKQKINDVATKHAWFVEDRFVKNELETKREHINFSASYLEHRIQNEHTVELLHVYLKEFSELIQKF
REIEKASSENFDEESDDAKNSIKVAE
Download Length: 321 bp
>T174618 NZ_CP081287:c179598-179317 [Pseudomonas aeruginosa]
ATGAGCCTGAAGTGGACCCGCAAGGCGGCCGCCGACCTGGACGCCATCTACGACCATTACGTCGTGCTGATCGGCCCGGA
AAAAGCTCTGAAAGCCGTTCAGGACATCGTCGAGCAGGTGAAACCGCTGCAGCAGGTAGCCAACCAGGGGGCAGGGCGGC
CCAGCGAGGTGCCAGGCGTACGCACCCTGACCCTGGAGCGCTGGCCGTTCAGCGCCCCGTTTCGGGTTAAAGGCAAGGAA
ATCCAGATTTTGCGCATCGATAGGGTCGAAATTACCCCCTGA
ATGAGCCTGAAGTGGACCCGCAAGGCGGCCGCCGACCTGGACGCCATCTACGACCATTACGTCGTGCTGATCGGCCCGGA
AAAAGCTCTGAAAGCCGTTCAGGACATCGTCGAGCAGGTGAAACCGCTGCAGCAGGTAGCCAACCAGGGGGCAGGGCGGC
CCAGCGAGGTGCCAGGCGTACGCACCCTGACCCTGGAGCGCTGGCCGTTCAGCGCCCCGTTTCGGGTTAAAGGCAAGGAA
ATCCAGATTTTGCGCATCGATAGGGTCGAAATTACCCCCTGA
Antitoxin
Download Length: 70 a.a. Molecular weight: 8252.31 Da Isoelectric Point: 4.3718
>AT174618 WP_001058486.1 NZ_CP062364:836169-836378 [Staphylococcus aureus]
MNNEQKEVIEHLVYQLELSVMNNLESYEHTEYVNGIEVVSEISREKHLELIMKWCAQELKNNFQLEKGE
MNNEQKEVIEHLVYQLELSVMNNLESYEHTEYVNGIEVVSEISREKHLELIMKWCAQELKNNFQLEKGE
Download Length: 210 bp
>AT174618 NZ_CP081287:c179822-179595 [Pseudomonas aeruginosa]
ATGAGCACCGTAGTCTCGTTCCGCGCCGATGACGCCCTGGTCGCGGCCCTCGACGAACTGGCCCGCGCCACCCACCGCGA
CCGCCCCTACCACCTGCGGCAGGCGCTCGCGCAGTACCTGGAAAGGCAGCAGTGGCAGGTCGCTGCCATCGATGAAGGCT
TGGCCGATGCCAATGCCGGTCGCCTGCTGGAACACACCGAGATCGAGAAGCGCTGGGGGCTGCAATGA
ATGAGCACCGTAGTCTCGTTCCGCGCCGATGACGCCCTGGTCGCGGCCCTCGACGAACTGGCCCGCGCCACCCACCGCGA
CCGCCCCTACCACCTGCGGCAGGCGCTCGCGCAGTACCTGGAAAGGCAGCAGTGGCAGGTCGCTGCCATCGATGAAGGCT
TGGCCGATGCCAATGCCGGTCGCCTGCTGGAACACACCGAGATCGAGAAGCGCTGGGGGCTGCAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|