Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 99461..100005 Replicon chromosome
Accession NZ_CP062255
Organism Xanthomonas sp. gxlp16

Toxin (Protein)


Gene name relE Uniprot ID H8FI26
Locus tag IG630_RS00430 Protein ID WP_003487886.1
Coordinates 99706..100005 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID H8FI25
Locus tag IG630_RS00425 Protein ID WP_003487884.1
Coordinates 99461..99718 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IG630_RS00410 94574..96061 - 1488 WP_011050071.1 ribonuclease H-like domain-containing protein -
IG630_RS00415 96058..98553 - 2496 WP_015462699.1 DEAD/DEAH box helicase -
IG630_RS00420 98731..99393 + 663 WP_005912558.1 hemolysin III family protein -
IG630_RS00425 99461..99718 + 258 WP_003487884.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IG630_RS00430 99706..100005 + 300 WP_003487886.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IG630_RS00440 100185..101084 - 900 WP_011050073.1 SDR family NAD(P)-dependent oxidoreductase -
IG630_RS00445 101144..101881 - 738 WP_003487890.1 SDR family oxidoreductase -
IG630_RS00450 102007..102918 + 912 WP_011050074.1 LysR family transcriptional regulator -
IG630_RS00455 103084..104157 - 1074 WP_040107715.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11231.97 Da        Isoelectric Point: 9.7235

>T174181 WP_003487886.1 NZ_CP062255:99706-100005 [Xanthomonas sp. WG16]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFGHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VVVHVMRSERALRGNRLSR

Download         Length: 300 bp

>T174181 NZ_CP080566:c2111425-2111249 [Staphylococcus aureus]
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGGTGGCATTACTGAAATCTTTAGAAAGGAGACGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9683.21 Da        Isoelectric Point: 9.8274

>AT174181 WP_003487884.1 NZ_CP062255:99461-99718 [Xanthomonas sp. WG16]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQARHRM
ARWLK

Download         Length: 258 bp

>AT174181 NZ_CP080566:2111118-2111259 [Staphylococcus aureus]
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGGCTATTTTAGATTAAA
GATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB H8FI26

Antitoxin

Source ID Structure
AlphaFold DB H8FI25

References