Detailed information of TA system TA174177

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ykfI-yfjZ/CbtA-CbeA
• Location: 1464307..1465032
• Replicon: chromosome
• Accession: NZ_CP062254
• Organism: Pectobacterium parmentieri strain QK-5

Toxin (Protein)

• Gene name: ykfI
• Uniprot ID: -
• Locus tag: IG623_RS06845
• Protein ID: WP_103808442.1
• Coordinates: 1464307..1464627 (-)
• Length: 107 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: IG623_RS06850
• Protein ID: WP_103808441.1
• Coordinates: 1464697..1465032 (-)
• Length: 112 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IG623_RS06815	1459510..1459800	-	291	WP_014699065.1	transposase	-
IG623_RS06820	1459866..1460195	+	330	Protein_1321	IS30 family transposase	-
IG623_RS06825	1460369..1460998	-	630	WP_103808445.1	hypothetical protein	-
IG623_RS06830	1461429..1462643	-	1215	WP_103808444.1	tyrosine-type recombinase/integrase	-
IG623_RS06835	1463004..1463174	-	171	WP_155116481.1	hypothetical protein	-
IG623_RS06840	1463356..1464189	-	834	WP_103808443.1	DUF4942 domain-containing protein	-
IG623_RS06845	1464307..1464627	-	321	WP_103808442.1	TA system toxin CbtA family protein	Toxin
IG623_RS06850	1464697..1465032	-	336	WP_103808441.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
IG623_RS06855	1465069..1465542	-	474	WP_121301511.1	DNA repair protein RadC	-
IG623_RS06860	1465626..1465859	-	234	WP_103808798.1	hypothetical protein	-
IG623_RS06865	1465877..1466350	-	474	WP_103808799.1	hypothetical protein	-
IG623_RS06870	1466386..1466955	-	570	Protein_1331	hypothetical protein	-
IG623_RS06875	1467137..1467835	-	699	WP_121247005.1	DeoR family transcriptional regulator	-
IG623_RS06880	1468205..1469080	-	876	WP_103808734.1	GTPase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1457241..1482770	25529

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-105)

Antitoxin

• Antitoxin CbeA (7-106)

Sequences

Toxin

Protein

• Length: 107 a.a.
• Molecular weight: 12035.73 Da
• Isoelectric Point: 4.7768

>T174177 WP_103808442.1 NZ_CP062254:c1464627-1464307 [Pectobacterium parmentieri]
MQTSPAIPPREDNPCPSPIAVWQQLLTYLLEKHYGLTLNDTPFCEENVIQEHIDAGITLANAVNFLVEKYELVRIDRNGF
NWQEQSPFLTAVDVLRARRATGLLKA

Nucleotide

• Length: 321 bp

>T174177 NZ_CP080566:c1606680-1606429 [Staphylococcus aureus]
ATGAATAATCGCGAAAAAATCGAACAGTCCGTTATTAGTGCTAGTGCGTATAACGGTAATGACACAGAGGGATTGCTAAA
AGAGATTGAGGACGTGTATAAGAAAGCACAAGCGTTTGATGAAATACTTGAGGGAATGACAAATGCTATTCAACATTCAG
TTAAAGAAGGTATTGAACTTGATGAAGCAGTAGGGATTATGACGGGGCAAGTGGTCTATAAATATGAGGAGGAGCAGGAA
AATGAGTATTAG

Antitoxin

Protein

• Length: 112 a.a.
• Molecular weight: 12643.32 Da
• Isoelectric Point: 5.5351

>AT174177 WP_103808441.1 NZ_CP062254:c1465032-1464697 [Pectobacterium parmentieri]
MPSSDTPEWGLKCAITPRFGARLVQEGHRLHYLEDRASIVGTFSEMEAHHLEEIFPELIKQLEQKLRSGELNPRQRGCVT
LYCNEWTCEADTLGSFGYVYIVIYPTSAATH

Nucleotide

• Length: 336 bp

>AT174177 NZ_CP080566:c1606439-1606266 [Staphylococcus aureus]
ATGAGTATTAGTGTAGGAGATAAAGTATATAACCATGAAACAAACGAAAGTCTAGAGATTGTGCAATTGGTCGGAGATAT
TAGAGATACACATTATAAACTGTCTGATGATTCAGTTATTAGCATTATAGATTTTATTACTAAACCAATTTATCTAATTA
AGGGGGACGAGTAA