Detailed information of TA system TA174174

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 561503..562030
• Replicon: chromosome
• Accession: NZ_CP062254
• Organism: Pectobacterium parmentieri strain QK-5

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: IG623_RS02760
• Protein ID: WP_039517502.1
• Coordinates: 561755..562030 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: IG623_RS02755
• Protein ID: WP_103808671.1
• Coordinates: 561503..561751 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IG623_RS02720	557546..557704	+	159	WP_155242703.1	hypothetical protein	-
IG623_RS02725	557851..558684	+	834	WP_103808667.1	hypothetical protein	-
IG623_RS02730	558742..559092	+	351	WP_005974477.1	hypothetical protein	-
IG623_RS02735	559215..559688	+	474	WP_103808668.1	DNA repair protein RadC	-
IG623_RS02740	559728..560063	+	336	WP_103808669.1	type IV toxin-antitoxin system YeeU family antitoxin	-
IG623_RS02745	560122..560442	+	321	WP_103808670.1	TA system toxin CbtA family protein	-
IG623_RS02750	560560..561393	+	834	Protein_535	DUF4942 domain-containing protein	-
IG623_RS02755	561503..561751	+	249	WP_103808671.1	ribbon-helix-helix domain-containing protein	Antitoxin
IG623_RS02760	561755..562030	+	276	WP_039517502.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
IG623_RS02765	562078..562590	+	513	WP_103808672.1	AAA family ATPase	-
IG623_RS02770	562897..564017	-	1121	Protein_539	IS3 family transposase	-
IG623_RS02775	564089..565257	+	1169	WP_103808047.1	IS3 family transposase	-
IG623_RS02780	565232..565543	-	312	WP_103808046.1	hypothetical protein	-
IG623_RS02785	566025..566287	-	263	Protein_542	PAAR domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	mgtB / hcp	539323..682094	142771

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (9-43)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 11028.25 Da
• Isoelectric Point: 5.5034

>T174174 WP_039517502.1 NZ_CP062254:561755-562030 [Pectobacterium parmentieri]
MEIRWTQKAQDDLERIYGFASQYSRHHADEVLDRLIIGTTGIADHPRIGVSQTRYEPREVRKILFDDYEVHYEIQHDTIY
IVDLWHTREDR

Nucleotide

• Length: 276 bp

>T174174 NZ_CP080566:821875-822192 [Staphylococcus aureus]
ATGAATTGGGAAATTAAAGATTTGATGTGTGATATTGAAGTGATAAAAGAAAAAATCAATGATGTAGCTATCAAACATGG
TTGGTTTGTTGAAGATAAATTTGTCAAAAATGAATTAGAAACAAAACAGGAACATATTAATTTTTCTGCTAGCTATTTAG
AACATCGTATACAAAATGAACATACAGTTGAGTTATTACAGGTGTACTTAAAAGAATTCGGTGAACTTATACAAAAGTTT
CATGAAATAGAAAAAGCATCATCTGAGAACTTTGGCGAGGAATCAGATGACGCAAAGAAATTAAAAATTACAGAGTAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9007.39 Da
• Isoelectric Point: 8.7560

>AT174174 WP_103808671.1 NZ_CP062254:561503-561751 [Pectobacterium parmentieri]
MGQPAKQTISAQIPAELAAAVESLAIELDRSKSWVIKEALTAMIEERERRHQRVLKGLADVDAGRVVSHADVIDFANKLK
KS

Nucleotide

• Length: 249 bp

>AT174174 NZ_CP080566:821663-821872 [Staphylococcus aureus]
ATGAATAATGAACAAAAAGAAGTAATAGAACACGTGGTTTATCAACTTGAGTTAAGTATCATGAATAATTTTGAAAGTTA
TGAACACACGGAATATGTTGATGGTATTGAAGTGGTTTCAGAGATCAGTCCTGAAAAGCACTTAGAATTGATAATGAAAT
GGTGCGCACAAGAATTAAAGAATAATTTTCAATTAGAAAAAGGAGAATAA