Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 559728..560442 Replicon chromosome
Accession NZ_CP062254
Organism Pectobacterium parmentieri strain QK-5

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag IG623_RS02745 Protein ID WP_103808670.1
Coordinates 560122..560442 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag IG623_RS02740 Protein ID WP_103808669.1
Coordinates 559728..560063 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IG623_RS02710 555448..556380 + 933 WP_103808665.1 hypothetical protein -
IG623_RS02715 556475..557362 + 888 WP_103808666.1 50S ribosome-binding GTPase -
IG623_RS02720 557546..557704 + 159 WP_155242703.1 hypothetical protein -
IG623_RS02725 557851..558684 + 834 WP_103808667.1 hypothetical protein -
IG623_RS02730 558742..559092 + 351 WP_005974477.1 hypothetical protein -
IG623_RS02735 559215..559688 + 474 WP_103808668.1 DNA repair protein RadC -
IG623_RS02740 559728..560063 + 336 WP_103808669.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
IG623_RS02745 560122..560442 + 321 WP_103808670.1 TA system toxin CbtA family protein Toxin
IG623_RS02750 560560..561393 + 834 Protein_535 DUF4942 domain-containing protein -
IG623_RS02755 561503..561751 + 249 WP_103808671.1 ribbon-helix-helix domain-containing protein -
IG623_RS02760 561755..562030 + 276 WP_039517502.1 type II toxin-antitoxin system RelE/ParE family toxin -
IG623_RS02765 562078..562590 + 513 WP_103808672.1 AAA family ATPase -
IG623_RS02770 562897..564017 - 1121 Protein_539 IS3 family transposase -
IG623_RS02775 564089..565257 + 1169 WP_103808047.1 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - mgtB / hcp 539323..682094 142771


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12049.71 Da        Isoelectric Point: 4.5971

>T174173 WP_103808670.1 NZ_CP062254:560122-560442 [Pectobacterium parmentieri]
MQTSPAIPPREDNPCPSPIAAWQQLLTYLLEKHYGLTLNDTPFCEENVIQEHIDAGITLVNAVNFLVEKYELVRIDRDGF
NWQEQSPFLTAVDVLRARRANGLLKA

Download         Length: 321 bp

>T174173 NZ_CP080564:c2472886-2472620 [Staphylococcus aureus]
ATGAGCAATTACACGGTTAAGATTAAAAATTCGGCGAAGTTAGATTTAAAGAAAATAAAACATCCTTATTTAAAGAAGAC
ATTTATAGAAATTGTTGAGACTTTAAAAAATAATCCTTATAAAATAACACAATCCTTTGAAAAATTAGAACCTAAATATT
TAGAGCGATATTCAAGAAGAATTAACCTTCAGCACAGGGTCGTCTATACCATAGATGATCGAAATAAAGTAGTATTAATA
CTATCGGCATGGTCACATTATGATTAA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12529.30 Da        Isoelectric Point: 5.8292

>AT174173 WP_103808669.1 NZ_CP062254:559728-560063 [Pectobacterium parmentieri]
MSLSDTPEWGLKSAITPRFGARLVQEGNRLHYLADRVSFIGTFSKTEAQSLERCFPELIKLLEQKLRMGELNPRQQGCIT
LYCNEWTCEADTLGSFGYVYIAIYPSSAATQ

Download         Length: 336 bp

>AT174173 NZ_CP080564:c2473143-2472886 [Staphylococcus aureus]
ATGATTATCACTAGCCCTACAGAAGCGAGAAAAGATTTTTATCAATTACTAAAAAATGTTAATAATAATCACGAACCAAT
TTATATTAGTGGTAATAATGCCGAAAATAATGCTGTGATTATAGGTTTAGAAGATTGGAAAAGTATACAAGAGACAATGT
ATCTTGTATCTACTGGTACAATGGACAAAGTAAGAGAAAGAGAAAAAGATAATAGTGGTACAACAAATATAGATGATATT
GATTGGGATAATCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References