Detailed information of TA system TA174171

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbDE/ParE-DnaT
• Location: 371155..371686
• Replicon: chromosome
• Accession: NZ_CP062254
• Organism: Pectobacterium parmentieri strain QK-5

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: -
• Locus tag: IG623_RS01760
• Protein ID: WP_103808553.1
• Coordinates: 371399..371686 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: stbD
• Uniprot ID: -
• Locus tag: IG623_RS01755
• Protein ID: WP_103808552.1
• Coordinates: 371155..371409 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IG623_RS01730	366373..366963	-	591	WP_011091952.1	DnaA initiator-associating protein DiaA	-
IG623_RS01735	367005..367361	-	357	WP_012822117.1	YraN family protein	-
IG623_RS01740	367358..369376	-	2019	WP_014698522.1	penicillin-binding protein activator	-
IG623_RS01745	369438..370325	+	888	WP_014698523.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
IG623_RS01755	371155..371409	+	255	WP_103808552.1	plasmid stabilization protein	Antitoxin
IG623_RS01760	371399..371686	+	288	WP_103808553.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
IG623_RS01765	371868..372656	+	789	WP_033072300.1	4,5-DOPA dioxygenase extradiol	-
IG623_RS01770	372744..373904	-	1161	WP_103808554.1	glutathionylspermidine synthase family protein	-
IG623_RS01775	373916..374584	-	669	WP_012822126.1	DUF1190 family protein	-
IG623_RS01780	374868..376259	-	1392	WP_012822127.1	outer membrane channel protein TolC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-87)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10997.89 Da
• Isoelectric Point: 10.7148

>T174171 WP_103808553.1 NZ_CP062254:371399-371686 [Pectobacterium parmentieri]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQVYSDTQGRSA

Nucleotide

• Length: 288 bp

>T174171 NZ_CP080564:c2416333-2416067 [Staphylococcus aureus]
ATGGCTAGGTTAAATATTACGTTTTCGCCTCAAGCCTTTGAAGATTATAAGTATTTTCAGCAGAACGATAAAAAAATGGT
GAAGAAGATTAATGAGTTACTTAAAAGTATTGACAGAAATGGTGCATTGGAAGGTATAGGTAAGCCTGAAAAGTTAAAAT
CGAATCTGACTGGGTATTATAGTAGACGTATCAATCACGAACATAGATTGGTTTATACAGTAGATGACAATCATATAAAA
ATAGCATCATGTAAATACCATTATTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9284.50 Da
• Isoelectric Point: 3.7947

>AT174171 WP_103808552.1 NZ_CP062254:371155-371409 [Pectobacterium parmentieri]
MAFNILTNTVASITELKRDPMGTVRSAEGETIAILNRNEPAFYCVPPAMFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Nucleotide

• Length: 255 bp

>AT174171 NZ_CP080564:c2416584-2416333 [Staphylococcus aureus]
ATGATTATTAAAAATTATTCATACGCTCGACAGAATTTAAAGGCACTTATGACAAAAGTAAATGATGATAGTGATATGGT
AACTGTAACATCTACTGATGATAAAAACGTAGTAATCATGTCAGAATCAGATTATAACTCCATGATGGAAACACTTTACC
TCCAACAGAACCCAAATAATGCTGAACACTTAGCTCAATCAATTGCAGATCTAGAACGTGGGAAAACTATAACGAAAGAT
ATAGATGTATAA