Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 371155..371686 Replicon chromosome
Accession NZ_CP062254
Organism Pectobacterium parmentieri strain QK-5

Toxin (Protein)


Gene name stbE Uniprot ID -
Locus tag IG623_RS01760 Protein ID WP_103808553.1
Coordinates 371399..371686 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID -
Locus tag IG623_RS01755 Protein ID WP_103808552.1
Coordinates 371155..371409 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IG623_RS01730 366373..366963 - 591 WP_011091952.1 DnaA initiator-associating protein DiaA -
IG623_RS01735 367005..367361 - 357 WP_012822117.1 YraN family protein -
IG623_RS01740 367358..369376 - 2019 WP_014698522.1 penicillin-binding protein activator -
IG623_RS01745 369438..370325 + 888 WP_014698523.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
IG623_RS01755 371155..371409 + 255 WP_103808552.1 plasmid stabilization protein Antitoxin
IG623_RS01760 371399..371686 + 288 WP_103808553.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IG623_RS01765 371868..372656 + 789 WP_033072300.1 4,5-DOPA dioxygenase extradiol -
IG623_RS01770 372744..373904 - 1161 WP_103808554.1 glutathionylspermidine synthase family protein -
IG623_RS01775 373916..374584 - 669 WP_012822126.1 DUF1190 family protein -
IG623_RS01780 374868..376259 - 1392 WP_012822127.1 outer membrane channel protein TolC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-87)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10997.89 Da        Isoelectric Point: 10.7148

>T174171 WP_103808553.1 NZ_CP062254:371399-371686 [Pectobacterium parmentieri]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQVYSDTQGRSA

Download         Length: 288 bp

>T174171 NZ_CP080564:c2416333-2416067 [Staphylococcus aureus]
ATGGCTAGGTTAAATATTACGTTTTCGCCTCAAGCCTTTGAAGATTATAAGTATTTTCAGCAGAACGATAAAAAAATGGT
GAAGAAGATTAATGAGTTACTTAAAAGTATTGACAGAAATGGTGCATTGGAAGGTATAGGTAAGCCTGAAAAGTTAAAAT
CGAATCTGACTGGGTATTATAGTAGACGTATCAATCACGAACATAGATTGGTTTATACAGTAGATGACAATCATATAAAA
ATAGCATCATGTAAATACCATTATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9284.50 Da        Isoelectric Point: 3.7947

>AT174171 WP_103808552.1 NZ_CP062254:371155-371409 [Pectobacterium parmentieri]
MAFNILTNTVASITELKRDPMGTVRSAEGETIAILNRNEPAFYCVPPAMFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Download         Length: 255 bp

>AT174171 NZ_CP080564:c2416584-2416333 [Staphylococcus aureus]
ATGATTATTAAAAATTATTCATACGCTCGACAGAATTTAAAGGCACTTATGACAAAAGTAAATGATGATAGTGATATGGT
AACTGTAACATCTACTGATGATAAAAACGTAGTAATCATGTCAGAATCAGATTATAACTCCATGATGGAAACACTTTACC
TCCAACAGAACCCAAATAATGCTGAACACTTAGCTCAATCAATTGCAGATCTAGAACGTGGGAAAACTATAACGAAAGAT
ATAGATGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References