Detailed information of TA system TA174166

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/Acetyltransf_9(toxin)
• Location: 2913532..2915242
• Replicon: chromosome
• Accession: NZ_CP062253
• Organism: Pseudomonas gozinkensis strain IzPS32d

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: IHQ43_RS12890
• Protein ID: WP_192564659.1
• Coordinates: 2913532..2914599 (-)
• Length: 356 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: IHQ43_RS12895
• Protein ID: WP_192564660.1
• Coordinates: 2914685..2915242 (-)
• Length: 186 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• 5'-deoxynucleotidase YfbR/HDDC2 (9-165)

Antitoxin

• Cro/C1-type helix-turn-helix domain (12-64)

Sequences

Toxin

Protein

• Length: 356 a.a.
• Molecular weight: 38963.98 Da
• Isoelectric Point: 4.8049

>T174166 WP_192564659.1 NZ_CP062253:c2914599-2913532 [Pseudomonas gozinkensis]
MNLEKIKGRLDFLREAERLKDVLRSAHTSSGRSESTAEHSWRLCLMAIVFADDLAGLDVLKVLKMCVIHDLGEAINGDIP
AVDQAGLPDKGEQERNDLLLLIRSLDDALRDEILALWDDYENASSPEAKAVKALDKLETLLQHTQGKNPPDFDYGFNLAY
GKQYTNADPLFETLRTLIDRDTRERMNTNITIRNERPEDIDAIARITEAAFQHEEHSSHTEHFIVNALRRAGQLSVSLVA
VENDTVVGHVAISPVTISSGAQGWYGLGPISVCPTRQQQGIGSALMKASLAQLQRIGGVGCVVLGDPGYYGRFGFKTHAG
LELPGIPAEYFQALAFEGELPVGVVSYHEAFDATA

Nucleotide

• Length: 1068 bp

>T174166 NZ_CP080564:c1873463-1873311 [Staphylococcus aureus]
ATGTCTAAAGACAAAGATCCAAAATTAAATTATCATGAAGAAGAAAACAGTATGGTAACGGATTTTGAAGATTTAAAAGA
ATTAGGTAAAGAAATGGAACAAATTTCTGATCAAAATGATCAAGAAAAGAATTCTGAAGAAGACAGTCAGTAA

Antitoxin

Protein

• Length: 186 a.a.
• Molecular weight: 20528.51 Da
• Isoelectric Point: 7.8760

>AT174166 WP_192564660.1 NZ_CP062253:c2915242-2914685 [Pseudomonas gozinkensis]
MSDTLLKPSLPGIALRRWRVLHRVKQSHAAELFKVTQSTISRWESGVQAMDPDAHLQLERLLAARLDSAADQALARLVTD
SARPVHLVCDLTHRLLACSPTRAAQFSSPLSDLLGQSLWRFATAQIQHKESLLDDTGWREVPAPPALEFVTGHNDSTLVP
IRESLCRWTRIALSDGTAARLVETL

Nucleotide

• Length: 558 bp

>AT174166 NZ_CP080564:c1874087-1873488 [Staphylococcus aureus]
ATGGCAATGAACTTTAAAGTCTTTGACAATAGTCAACTTGTAGCAGAATATGCTGCTGATATTATTAGAAAGCAATTTAA
CAATAATCCTACTACAATTGCAGGTTTTCATTTAGATACAGATCAAGCGCCAGTTCTAGATGAATTAAAGAAAAATGTTG
AAAAACATGCTGTTGATTTTAGCCAAATAAATATTTTAGATTATGACGATAAAAAATCATATTTCGAAGGGTTAGGTGTA
CCAGCAGGTCAAGTTTATCCAATTGCTTATGAAAAAGATGCAATCGAATTAATCGCTGATAAGATTAAAACTAAAGAAAA
TAAAGGGAAATTAACATTACAAGTTGTTTCTATCGATGAGCAAGGTAAGTTAAATGTTAGTATTCGTCAAGGACTAATGG
AAGCAAGAGAAATTTTCTTAGTAGTGACAGGTGCTAATAAACGAGATGTAGTTGAAAAATTATATCAAGAAAATGGTAAA
ACAAGCTTCGAACCAGCCGATTTAAAAGCACATAGAATGGTAAATGTTATTCTTGATAAAGAAGCGGCTGCAGGTTTACC
TGAAGATGTTAAAGCTTACTTTACGTCACGCTTTGCTTAA