174164

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 1841099..1842151 Replicon chromosome
Accession NZ_CP062253
Organism Pseudomonas gozinkensis strain IzPS32d

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag IHQ43_RS08305 Protein ID WP_192564016.1
Coordinates 1841099..1841602 (-) Length 168 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag IHQ43_RS08310 Protein ID WP_192564017.1
Coordinates 1841684..1842151 (-) Length 156 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IHQ43_RS08280 1836426..1838414 + 1989 WP_011333087.1 heme lyase CcmF/NrfE family subunit -
IHQ43_RS08285 1838411..1838947 + 537 WP_192564015.1 DsbE family thiol:disulfide interchange protein -
IHQ43_RS08290 1838944..1839414 + 471 WP_011333089.1 cytochrome c-type biogenesis protein CcmH -
IHQ43_RS08295 1839411..1840613 + 1203 WP_007959249.1 c-type cytochrome biogenesis protein CcmI -
IHQ43_RS08300 1840639..1841046 + 408 WP_085605822.1 hypothetical protein -
IHQ43_RS08305 1841099..1841602 - 504 WP_192564016.1 PIN domain-containing protein Toxin
IHQ43_RS08310 1841684..1842151 - 468 WP_192564017.1 helix-turn-helix domain-containing protein Antitoxin
IHQ43_RS08315 1842424..1842651 + 228 Protein_1638 type II toxin-antitoxin system HicB family antitoxin -
IHQ43_RS08320 1842698..1843885 - 1188 WP_192564018.1 MFS transporter -
IHQ43_RS08325 1844127..1844747 + 621 WP_192564019.1 hypothetical protein -
IHQ43_RS08330 1844803..1845801 - 999 WP_127797317.1 sulfate ABC transporter substrate-binding protein -
IHQ43_RS08335 1845908..1846732 - 825 WP_192564020.1 ion transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-91)

Antitoxin

SinI-like, DNA-binding domain

(84-130)


Sequences

Toxin        


Download         Length: 168 a.a.        Molecular weight: 18764.62 Da        Isoelectric Point: 5.5879

>T174164 WP_192564016.1 NZ_CP062253:c1841602-1841099 [Pseudomonas gozinkensis]
MWLALSGRFRARWTQEIHCEWKRNLLKNRPDLTMEQLDRTSGLMDQAIPDACVHDYEDLIAGLTLPDCDDRHVLAAAIRC
GASVIVTFNQKDFPCKALEPFGIEAQHPDEFVDNLLGLDPAAVVAAAQKQRRQLKMPAMDVEPFLDLLQRQGLIKSAQAL
SGYHAIL

Download         Length: 504 bp

>T174164 NZ_CP080564:c833652-833464 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTGGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA

Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17287.67 Da        Isoelectric Point: 6.4962

>AT174164 WP_192564017.1 NZ_CP062253:c1842151-1841684 [Pseudomonas gozinkensis]
MSTVIHPSISLPVEREVKAAIEGQRALAAYLATHFETQHIQIFDEQNEAHRVELPTSALRLLIDILAEQAAGNAVQVVPV
HAELTTQEAADLLNVSRPHLIKLLESGELSYHKTGKHRRVRFADLMDYKTRRTTASEQAMALLAEQAQALRTGYE

Download         Length: 468 bp

>AT174164 NZ_CP080564:c833941-833681 [Staphylococcus aureus]
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATCGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTCTATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References