Detailed information of TA system TA174164

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 1841099..1842151
• Replicon: chromosome
• Accession: NZ_CP062253
• Organism: Pseudomonas gozinkensis strain IzPS32d

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: IHQ43_RS08305
• Protein ID: WP_192564016.1
• Coordinates: 1841099..1841602 (-)
• Length: 168 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: -
• Locus tag: IHQ43_RS08310
• Protein ID: WP_192564017.1
• Coordinates: 1841684..1842151 (-)
• Length: 156 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (3-91)

Antitoxin

• SinI-like, DNA-binding domain (84-130)

Sequences

Toxin

Protein

• Length: 168 a.a.
• Molecular weight: 18764.62 Da
• Isoelectric Point: 5.5879

>T174164 WP_192564016.1 NZ_CP062253:c1841602-1841099 [Pseudomonas gozinkensis]
MWLALSGRFRARWTQEIHCEWKRNLLKNRPDLTMEQLDRTSGLMDQAIPDACVHDYEDLIAGLTLPDCDDRHVLAAAIRC
GASVIVTFNQKDFPCKALEPFGIEAQHPDEFVDNLLGLDPAAVVAAAQKQRRQLKMPAMDVEPFLDLLQRQGLIKSAQAL
SGYHAIL

Nucleotide

• Length: 504 bp

>T174164 NZ_CP080564:c833652-833464 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTGGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA

Antitoxin

Protein

• Length: 156 a.a.
• Molecular weight: 17287.67 Da
• Isoelectric Point: 6.4962

>AT174164 WP_192564017.1 NZ_CP062253:c1842151-1841684 [Pseudomonas gozinkensis]
MSTVIHPSISLPVEREVKAAIEGQRALAAYLATHFETQHIQIFDEQNEAHRVELPTSALRLLIDILAEQAAGNAVQVVPV
HAELTTQEAADLLNVSRPHLIKLLESGELSYHKTGKHRRVRFADLMDYKTRRTTASEQAMALLAEQAQALRTGYE

Nucleotide

• Length: 468 bp

>AT174164 NZ_CP080564:c833941-833681 [Staphylococcus aureus]
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATCGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTCTATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA