Detailed information of TA system TA174159

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 3758629..3759097
• Replicon: chromosome
• Accession: NZ_CP062252
• Organism: Pseudomonas allokribbensis strain IzPS23

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: IF199_RS17035
• Protein ID: WP_208491912.1
• Coordinates: 3758813..3759097 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: IF199_RS17030
• Protein ID: WP_192558187.1
• Coordinates: 3758629..3758823 (+)
• Length: 65 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF199_RS17010	3754250..3755218	-	969	WP_192558183.1	Gfo/Idh/MocA family oxidoreductase	-
IF199_RS17015	3755235..3756122	-	888	WP_192558184.1	Dyp-type peroxidase	-
IF199_RS17020	3756180..3757214	-	1035	WP_192558185.1	AraC family transcriptional regulator	-
IF199_RS17025	3757426..3758373	+	948	WP_192558186.1	transporter	-
IF199_RS17030	3758629..3758823	+	195	WP_192558187.1	stability determinant	Antitoxin
IF199_RS17035	3758813..3759097	+	285	WP_208491912.1	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	Toxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10793.33 Da
• Isoelectric Point: 10.1273

>T174159 WP_208491912.1 NZ_CP062252:3758813-3759097 [Pseudomonas allokribbensis]
MLLEWSDQALNDLADIIDYIEQYNSNASVALQHKVGAATKRLSSIPYGYRSGRVPSTREMVINPNYLLVYRVNGRIRILT
LVHTRRQYPRTSSP

Nucleotide

• Length: 285 bp

>T174159 NZ_CP080562:c2170869-2170543 [Staphylococcus aureus]
ATGAATCGGGAAATTAAAGATTTATTTAGCGATTTAAAGTTGTTGAAAGATAGTTTTGAGGATTTAAAGGATAGTAATGG
TTGGCATTTTGATGAGCTATATCCATATGAACCAAATCATGTCTTAAATAAAGATGAATTAATTGGAGAGGGATTTTCTT
ATCATGAGAGACGTATTCACAATAATCAAATGTTTGATTTATTCCATCTCTATATAGAGCAGTTCGATAATATTATCGAA
AAGTTTTATGAAATAGAAAAAGCATCATCTGAGAACTTTGGCGAGGAATCAGATGACGCAAAGAATTCAATAAAAGTAGC
AGAGTAA

Antitoxin

Protein

• Length: 65 a.a.
• Molecular weight: 7519.37 Da
• Isoelectric Point: 4.3431

>AT174159 WP_192558187.1 NZ_CP062252:3758629-3758823 [Pseudomonas allokribbensis]
MSILHSPFYSDFESEEEAESYDRWFRAKVQEALDDPSPGIPHDEAMAMLDQMLEEMRRKRRAAA

Nucleotide

• Length: 195 bp

>AT174159 NZ_CP080562:c2171081-2170872 [Staphylococcus aureus]
ATGAATAATGAACAAAAAGAAGTAATAGAACACGTGGTTTATCAACTTGAGTTAAGTGTCGTGAATAATTTGGAAAGTTA
TGAACACACAGAATATGTTAATGGTATTGAAGTGGTTTCAGAGATCAGTCGTGAAAAGCACTTAGAATTGATAATGAAAT
GGTGCGCACAAGAATTAAAGAATAATTTTCAATTAGAGAAAGGAGAATAA