Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3661034..3661553 Replicon chromosome
Accession NZ_CP062252
Organism Pseudomonas allokribbensis strain IzPS23

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IF199_RS16640 Protein ID WP_192558137.1
Coordinates 3661034..3661315 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IF199_RS16645 Protein ID WP_192560964.1
Coordinates 3661305..3661553 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IF199_RS16610 3656440..3657204 - 765 WP_192560963.1 IclR family transcriptional regulator -
IF199_RS16615 3657283..3657672 - 390 WP_192558136.1 RidA family protein -
IF199_RS16620 3657704..3658501 - 798 WP_007960239.1 amino acid ABC transporter ATP-binding protein -
IF199_RS16625 3658498..3659160 - 663 WP_007960241.1 amino acid ABC transporter permease -
IF199_RS16630 3659170..3659832 - 663 WP_059405928.1 amino acid ABC transporter permease -
IF199_RS16635 3659884..3660732 - 849 WP_102622731.1 transporter substrate-binding domain-containing protein -
IF199_RS16640 3661034..3661315 - 282 WP_192558137.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IF199_RS16645 3661305..3661553 - 249 WP_192560964.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IF199_RS16650 3661868..3662299 + 432 WP_192558138.1 thioredoxin family protein -
IF199_RS16655 3662474..3663628 + 1155 WP_192558139.1 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) -
IF199_RS16660 3663625..3665799 + 2175 WP_192558140.1 phage adsorption protein NrfB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10949.84 Da        Isoelectric Point: 10.3168

>T174158 WP_192558137.1 NZ_CP062252:c3661315-3661034 [Pseudomonas allokribbensis]
MTYELEFSEKAWKEWKKLDANLKEQLKKKLQERLENPHVPADRLRGLGGAYKIKLRNVGYRLVYRVKDEVLIVTVIAIGK
REGGYVYKIATER

Download         Length: 282 bp

>T174158 NZ_CP080562:c2053971-2053819 [Staphylococcus aureus]
ATGTCTAAAGACAAAGATCCAAAATTAAATTATCATGAAGAAGAAAACAGTATGGTAACGGATTTTGAAGATTTAAAAGA
ATTAGGTAAAGAAATGGAACAAATCTCTGATCAAAATGATCAAGAAAAAAATTCTGAAGAAGACAGTCAGTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8916.35 Da        Isoelectric Point: 4.7360

>AT174158 WP_192560964.1 NZ_CP062252:c3661553-3661305 [Pseudomonas allokribbensis]
MTHIVLSQVVASISELKKNPMGTVAAGGGDSVAILNRNEPAFYCVPAKAYEALMNRLEDLELIALCKEREKDPTIKVSID
DL

Download         Length: 249 bp

>AT174158 NZ_CP080562:c2054595-2053996 [Staphylococcus aureus]
ATGGCAATGAACTTTAAAGTCTTTGACAATAGTCAACTTGTAGCAGAATATGCTGCTGATATTATTAGAAAGCAATTTAA
CAATAATCCTACTACAATTGCAGGTTTTCATTTAGATACAGATCAAGCGCCAGTTCTAGATGAATTAAAGAAAAATGTTG
AAAAACATGCTGTTGATTTTAGCCAAATAAATATTTTAGATTATGACGATAAAAAATCATATTTCGAAGCGTTAGGTGTA
CCAGCAGGTCAAGTTTATCCAATTGCTTATGAAAAAGATGCAATCGAATTAATCGCTGATAAGATTAAAACTAAAGAAAA
TAAAGGGAAATTAACATTACAAGTTGTTTCTATCGATGAGCAAGGTAAGTTAAATGTTAGTATTCGTCAAGGACTAATGG
AAGCAAGAGAAATTTTCTTAGTAGTGACAGGTGCTAATAAACGAGATGTAGTTGAAAAATTATATCAAGAAAATGGTAAA
ACAAGCTTCGAACCAGCCGATTTAAAAGCACATAGAATGGTAAATGTTATTCTTGATAAAGAAGCGGCTGCAGGTTTACC
TGAAGATGTTAAAGCTTACTTTACGTCACGCTTTGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References