Detailed information of TA system TA174151

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 3543432..3543900
• Replicon: chromosome
• Accession: NZ_CP062251
• Organism: Pseudomonas sp. IzPS59

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: IF189_RS15820
• Protein ID: WP_085710148.1
• Coordinates: 3543616..3543900 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: IF189_RS15815
• Protein ID: WP_085710147.1
• Coordinates: 3543432..3543626 (+)
• Length: 65 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF189_RS15795	3539060..3540028	-	969	WP_192551861.1	Gfo/Idh/MocA family oxidoreductase	-
IF189_RS15800	3540038..3540925	-	888	WP_134826484.1	Dyp-type peroxidase	-
IF189_RS15805	3540983..3542017	-	1035	WP_192551862.1	AraC family transcriptional regulator	-
IF189_RS15810	3542229..3543176	+	948	WP_134826483.1	transporter	-
IF189_RS15815	3543432..3543626	+	195	WP_085710147.1	stability determinant	Antitoxin
IF189_RS15820	3543616..3543900	+	285	WP_085710148.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10712.12 Da
• Isoelectric Point: 9.6587

>T174151 WP_085710148.1 NZ_CP062251:3543616-3543900 [Pseudomonas sp. IzPS59]
MPLEWSEQALDDLADIIDYVEQYNSNASTALQHKVGAATQRLSSIPYGYRSGRVPGTREMVVNPNYLLVYRVNGRIKILT
LVHTRRQYPRTSST

Nucleotide

• Length: 285 bp

>T174151 NZ_CP080560:c878660-878472 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTGGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA

Antitoxin

Protein

• Length: 65 a.a.
• Molecular weight: 7596.38 Da
• Isoelectric Point: 4.4791

>AT174151 WP_085710147.1 NZ_CP062251:3543432-3543626 [Pseudomonas sp. IzPS59]
MSILHSPFYSDFDSEEEAESYDRWFRAKVQEALDDPNPGIPHEEAMMRLDQLLEERRKNRRAAA

Nucleotide

• Length: 195 bp

>AT174151 NZ_CP080560:c878949-878689 [Staphylococcus aureus]
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATCGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTCTATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA