Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2292608..2293085 Replicon chromosome
Accession NZ_CP062251
Organism Pseudomonas sp. IzPS59

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IF189_RS10360 Protein ID WP_192553225.1
Coordinates 2292608..2292904 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IF189_RS10365 Protein ID WP_143492997.1
Coordinates 2292894..2293085 (-) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IF189_RS10320 2287614..2288087 + 474 WP_119427956.1 type II secretion system GspH family protein -
IF189_RS10325 2288093..2288467 + 375 WP_085712077.1 type II secretion system GspH family protein -
IF189_RS10330 2288442..2288993 + 552 WP_134826177.1 type II secretion system GspH family protein -
IF189_RS10335 2288990..2289382 + 393 WP_134826178.1 curli production assembly/transport protein CsgE -
IF189_RS10340 2289379..2289810 + 432 WP_134826179.1 curli production assembly protein CsgF -
IF189_RS10345 2289840..2290700 + 861 WP_192553222.1 curli production assembly/transport protein CsgG -
IF189_RS10350 2291741..2292121 + 381 WP_192553223.1 hypothetical protein -
IF189_RS10355 2292196..2292423 + 228 WP_192553224.1 antitoxin -
IF189_RS10360 2292608..2292904 - 297 WP_192553225.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IF189_RS10365 2292894..2293085 - 192 WP_143492997.1 antitoxin Antitoxin
IF189_RS10370 2293369..2294820 - 1452 WP_134826194.1 curlin -
IF189_RS10375 2294847..2295308 - 462 WP_134826195.1 curlin -
IF189_RS10380 2295363..2297597 - 2235 WP_192553226.1 cadherin-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11137.72 Da        Isoelectric Point: 8.9051

>T174149 WP_192553225.1 NZ_CP062251:c2292904-2292608 [Pseudomonas sp. IzPS59]
MQVEWQPEARAELLHILDYISDRNFKAANKLSNAIEAATVTLTKHPHLYRVGRTPGTREMVVHPNYLLIYQAVGRINILG
VVHARQEYPSCGARSQNE

Download         Length: 297 bp

>T174149 NZ_CP080556:c2605266-2605159 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7044.10 Da        Isoelectric Point: 4.6094

>AT174149 WP_143492997.1 NZ_CP062251:c2293085-2292894 [Pseudomonas sp. IzPS59]
MIDPLCPVVSDLGPEEQAASYDRWLIAKIQASMNDPRPSIPNDQVMAEMHALMEAKRKKYDAG

Download         Length: 192 bp

>AT174149 NZ_CP080556:2605082-2605142 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References