Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 4229857..4230646 Replicon chromosome
Accession NZ_CP062231
Organism Rhizobium sp. TH2

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag IHQ71_RS20935 Protein ID WP_258158360.1
Coordinates 4229857..4230363 (-) Length 169 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag IHQ71_RS20940 Protein ID WP_258158361.1
Coordinates 4230356..4230646 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IHQ71_RS20915 (IHQ71_20845) 4225721..4226932 - 1212 WP_258158357.1 efflux RND transporter periplasmic adaptor subunit -
IHQ71_RS20920 (IHQ71_20850) 4227326..4228384 - 1059 WP_258158358.1 ornithine cyclodeaminase -
IHQ71_RS20925 (IHQ71_20855) 4228381..4229304 - 924 WP_258158359.1 arginase -
IHQ71_RS20930 (IHQ71_20860) 4229423..4229860 + 438 WP_258162899.1 Lrp/AsnC family transcriptional regulator -
IHQ71_RS20935 (IHQ71_20865) 4229857..4230363 - 507 WP_258158360.1 GNAT family N-acetyltransferase Toxin
IHQ71_RS20940 (IHQ71_20870) 4230356..4230646 - 291 WP_258158361.1 DUF1778 domain-containing protein Antitoxin
IHQ71_RS20945 (IHQ71_20875) 4230687..4231124 - 438 WP_258158362.1 hypothetical protein -
IHQ71_RS20950 (IHQ71_20880) 4231181..4232383 - 1203 WP_258158363.1 phosphoglycerate kinase -
IHQ71_RS20955 (IHQ71_20885) 4232460..4234256 - 1797 WP_258158364.1 potassium/proton antiporter -
IHQ71_RS20960 (IHQ71_20890) 4234512..4235519 - 1008 WP_258158365.1 type I glyceraldehyde-3-phosphate dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4229857..4240187 10330


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(85-155)

Antitoxin

Vibrio phage ICP1, Orf50

(12-78)


Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 18540.34 Da        Isoelectric Point: 7.9474

>T173627 WP_258158360.1 NZ_CP062231:c4230363-4229857 [Rhizobium sp. TH2]
MADQARFDHPVVIDPDHDLLSFQCGEPILDDWLKTRALKNLALGASRTFVTCHAGSNRVVGYYALSMGSLFAIDTPGSIR
RNMPEIIPSVVLGRLAIDETAQGHGLGAALLHDAVNRSLVASQNVSARLVVVHAISQRAEQFYLRFGFVRMPVEDRTLAL
DLVKYQKR

Download         Length: 507 bp

>T173627 NZ_CP080253:2682228-2682335 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10576.89 Da        Isoelectric Point: 5.1037

>AT173627 WP_258158361.1 NZ_CP062231:c4230646-4230356 [Rhizobium sp. TH2]
MAGQPETSEVNIHLRARSGDRDLIDRAANISGTNRSQFMLSSALKEATNVLLDQTMIRLDAEAFQKVLTWMDAVPSEAES
KGIDRLKSVKSDWANG

Download         Length: 291 bp

>AT173627 NZ_CP080253:c2682181-2682115 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References