Detailed information of TA system TA173623

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-dinJ/YafQ-RelB
• Location: 1372278..1372809
• Replicon: chromosome
• Accession: NZ_CP062231
• Organism: Rhizobium sp. TH2

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: IHQ71_RS07005
• Protein ID: WP_258161229.1
• Coordinates: 1372278..1372559 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: dinJ
• Uniprot ID: -
• Locus tag: IHQ71_RS07010
• Protein ID: WP_258161230.1
• Coordinates: 1372546..1372809 (-)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IHQ71_RS06975 (IHQ71_06950)	1367879..1368526	+	648	WP_258161223.1	hypothetical protein	-
IHQ71_RS06980 (IHQ71_06955)	1368601..1368912	+	312	WP_258161224.1	Dabb family protein	-
IHQ71_RS06985 (IHQ71_06960)	1368999..1370156	+	1158	WP_258161225.1	phage portal protein	-
IHQ71_RS06990 (IHQ71_06965)	1370289..1370645	+	357	WP_258161226.1	ribonuclease E inhibitor RraB	-
IHQ71_RS06995 (IHQ71_06970)	1370655..1371629	-	975	WP_258161227.1	2-oxoglutarate and iron-dependent oxygenase domain-containing protein	-
IHQ71_RS07000 (IHQ71_06975)	1371965..1372276	+	312	WP_258161228.1	DUF6107 family protein	-
IHQ71_RS07005 (IHQ71_06980)	1372278..1372559	-	282	WP_258161229.1	type II toxin-antitoxin system YafQ family toxin	Toxin
IHQ71_RS07010 (IHQ71_06985)	1372546..1372809	-	264	WP_258161230.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
IHQ71_RS07015 (IHQ71_06990)	1372866..1373705	-	840	WP_258161231.1	AraC family transcriptional regulator	-
IHQ71_RS07020 (IHQ71_06995)	1373814..1374380	+	567	WP_258161232.1	HK97 family phage prohead protease	-
IHQ71_RS07025 (IHQ71_07000)	1374405..1375658	+	1254	WP_258161233.1	phage major capsid protein	-
IHQ71_RS07030 (IHQ71_07005)	1375724..1375948	-	225	WP_258162763.1	DUF4189 domain-containing protein	-
IHQ71_RS07035 (IHQ71_07010)	1376135..1376704	+	570	WP_258161234.1	head-tail connector protein	-
IHQ71_RS07040 (IHQ71_07015)	1376704..1377033	+	330	WP_258161235.1	phage head closure protein	-
IHQ71_RS07045 (IHQ71_07020)	1377035..1377430	+	396	WP_258161236.1	DUF3168 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1361033..1385583	24550

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (1-91)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (4-79)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10759.49 Da
• Isoelectric Point: 9.1063

>T173623 WP_258161229.1 NZ_CP062231:c1372559-1372278 [Rhizobium sp. TH2]
MRKIEPTSAFKRDFKREAKGRHAKVLQSELPALLLLLATDLPLEARLRDHALTGEWKDHRDCHVRPDLVLIYRKPDEETL
QLVRLGSHSELGL

Nucleotide

• Length: 282 bp

>T173623 NZ_CP080253:2000981-2001084 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9241.60 Da
• Isoelectric Point: 4.5388

>AT173623 WP_258161230.1 NZ_CP062231:c1372809-1372546 [Rhizobium sp. TH2]
MASNALVQTRIDGKVKDEASAVLAAMGLTVSDAVRLMLTRVAHDKALPFEPLIPNAETVAAMREARAGNLKSYESVDALM
ADLNAED

Nucleotide

• Length: 264 bp

>AT173623 NZ_CP080253:c2001122-2000851 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT