173621

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/Tad-HTH_37
Location 1110656..1111359 Replicon chromosome
Accession NZ_CP062231
Organism Rhizobium sp. TH2

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag IHQ71_RS05650 Protein ID WP_258160976.1
Coordinates 1110985..1111359 (-) Length 125 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag IHQ71_RS05645 Protein ID WP_258160975.1
Coordinates 1110656..1110973 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IHQ71_RS05625 (IHQ71_05615) 1105829..1106788 + 960 WP_258160971.1 hypothetical protein -
IHQ71_RS05630 (IHQ71_05620) 1107001..1108134 - 1134 WP_258160972.1 TauD/TfdA family dioxygenase -
IHQ71_RS05635 (IHQ71_05625) 1108274..1109158 + 885 WP_258160973.1 LysR substrate-binding domain-containing protein -
IHQ71_RS05640 (IHQ71_05630) 1109167..1110582 - 1416 WP_258160974.1 metalloprotease TldD -
IHQ71_RS05645 (IHQ71_05635) 1110656..1110973 - 318 WP_258160975.1 helix-turn-helix transcriptional regulator Antitoxin
IHQ71_RS05650 (IHQ71_05640) 1110985..1111359 - 375 WP_258160976.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IHQ71_RS05655 (IHQ71_05645) 1111414..1111935 - 522 WP_258160977.1 invasion associated locus B family protein -
IHQ71_RS05660 (IHQ71_05650) 1112332..1113219 + 888 WP_258160978.1 cytochrome c oxidase subunit II -
IHQ71_RS05665 (IHQ71_05655) 1113244..1114932 + 1689 WP_258160979.1 cytochrome c oxidase subunit I -
IHQ71_RS05670 (IHQ71_05660) 1114996..1115952 + 957 WP_258160980.1 heme o synthase -
IHQ71_RS05675 (IHQ71_05665) 1115954..1116097 + 144 WP_258163016.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(22-113)

Antitoxin

HigA2-like, helix-turn-helix domain

(10-89)


Sequences

Toxin        


Download         Length: 125 a.a.        Molecular weight: 13947.88 Da        Isoelectric Point: 9.8863

>T173621 WP_258160976.1 NZ_CP062231:c1111359-1110985 [Rhizobium sp. TH2]
MTKPPFQYGEKPLHWVGSSKRDFMAFPQEVISGMGYALGLAQLGGKHPHAKPWKGEGPGVLEIVENHDGDTYRAVYTVRF
EAAIYVLHAFQKKSPSGIRTATSDIDLIGERLKRAREDHERSRK

Download         Length: 375 bp

>T173621 NZ_CP080253:1835029-1835280 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11626.42 Da        Isoelectric Point: 10.1468

>AT173621 WP_258160975.1 NZ_CP062231:c1110973-1110656 [Rhizobium sp. TH2]
MDIEYGSTNVFADLGLPDAVGRQTKTRLALEINTILKGRKLRQTSAASLLGIPQSKVSALVNYRLEGFSVERLMGFLTSL
NQDIEIMIRPSRSEKEGHVSVHALR

Download         Length: 318 bp

>AT173621 NZ_CP080253:1835277-1835531 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References